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A 3-year-old boy presented with an unusual combination of indurated skin, sclerotic plaques with lichenification, and yellowish papules. Histopathology revealed diffuse dermal mucin deposits, and laboratory tests showed a positive throat culture for Group A streptococcus and elevated serum anti-streptolysin titers. An 10-day course of oral amoxicillin was associated with near-complete resolution of all dermatological findings within 4 months.

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The prevention and treatment of Rheumatic Heart disease is hinged on antibiotic administration in children with Group A (GAS) pharyngitis and Acute Rheumatic Fever (ARF). The Upper Limit of Normal (ULN) for serum Anti-streptolysin O titre (ASOT) has been employed as proof of antecedent GAS pharyngitis to fulfil the Jones' criteria for diagnosis of ARF. This value has not been generated among West African children.

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Background: Pneumococcal vaccines have been available worldwide since the early 2000s; consequently, few reports exist of poststreptococcal acute glomerulonephritis (PSAGN) or complications of pneumococcal infection. We describe a patient with PSAGN and bacteremia with Streptococcus pneumoniae serotype 22F (not covered by the 13-valent pneumococcal vaccine (PCV 13)).

Case Diagnosis/treatment: A 5-year-old boy received the PCV13 vaccine and was admitted to our hospital with a fever and gross hematuria.

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Post-streptococcal myositis - ultrasound features of an under-recognised disorder: a case report.

BMC Musculoskelet Disord

October 2024

Department of Nephrology, Hypertensiology and Rheumatology, Sana Klinikum Offenbach GmbH, Starkenburgring 66, 63069, Offenbach, Germany.

Article Synopsis
  • Post-streptococcal myalgia and myositis are rare complications associated with streptococcal infections, and there is limited data available about them, especially in terms of clinical imaging.* -
  • A case study of a 31-year-old woman revealed significant muscle pain and changes in her thigh after a streptococcal throat infection and was diagnosed with post-streptococcal myositis through various lab tests and imaging techniques.* -
  • This case marks the first report of ultrasound findings in this condition, suggesting that muscle ultrasound can be an effective tool for diagnosing post-streptococcal myalgia and myositis.*
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Article Synopsis
  • - The study investigates the use of AI, specifically ChatGPT, in the follow-up care of children diagnosed with acute post-streptococcal glomerulonephritis (APSGN), a common kidney condition caused by streptococcus infection.
  • - Researchers analyzed 11 pediatric patients with APSGN, noting their clinical characteristics and evaluating the accuracy of ChatGPT's responses to specific medical questions about the condition and its management.
  • - Findings suggest that ChatGPT provides accurate information regarding APSGN and can assist clinicians in decision-making and treatment planning for affected patients, potentially improving patient management.
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