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A Novel Potent Sleep-Promoting Effect of Turmeric: Turmeric Increases Non-Rapid Eye Movement Sleep in Mice Via Histamine HReceptor Blockade.
Mol Nutr Food Res
July 2021
Department of Food Science and Technology/Institute of Food Science, Pukyong National University, Busan, 48513, Republic of Korea.
Article Synopsis
- This study explores the sleep-promoting effects of turmeric, which haven't been previously reported, aiming to understand how it impacts sleep and its underlying molecular mechanisms.* -
- Using a variety of tests on mice, the study finds that turmeric extract (TE) significantly decreases the time it takes to fall asleep and enhances non-rapid eye movement sleep (NREMS), similar to the effects of diazepam.* -
- The research suggests that TE promotes sleep by blocking histamine H receptors, indicating its potential as a treatment for insomnia.*
Human bone marrow as a tissue in post-mortem identification and determination of psychoactive Substances-Screening methodology.
J Chromatogr B Analyt Technol Biomed Life Sci
September 2017
Laboratory for Forensic Chemistry, Department of Analytical Chemistry, Jagiellonian University, 3 Ingardena St., 30-060 Kraków, Poland.
The aim of this study was to apply a new instrumental approach to the analysis of human bone marrow for forensic purposes. A new screening method for the detection of more than 30 psychoactive drugs in bone marrow was developed and applied to case samples. The drugs used in this study belonged to the following groups: benzodiazepines (BZDs, n=16), tricyclic antidepressants (TCAs, n=5), selective serotonin reuptake inhibitors (SSRI, n=4), serotonin-norepinephrine reuptake inhibitors (n=1), anticonvulsants (n=1), imidazopyridines (n=1) and piperazines (n=3).
View Article and Find Full Text PDFInappropriate prescribing in older persons: A systematic review of medications available in different criteria.
Arch Gerontol Geriatr
July 2017
Division of Geriatrics, School of Medicine, Federal University of Juiz de Fora, Brazil.
Objective: The present study aims to systematically review all potentially inappropriate medications for older persons included in prescribing criteria published in the last decade.
Methods: A systematic review of published studies was performed. Articles describing the development of criteria for PIM Use in Older Adults published in the last decade and which provided a list of medications that should be considered inappropriate were included.
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