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Controlled Stimulus-Responsive Delivery Systems for Osteoarthritis Treatment.
Int J Mol Sci
November 2024
School of Medical Information Engineering, Gannan Medical University, Ganzhou 341000, China.
Osteoarthritis (OA), a common and disabling degenerative joint disease, affects millions of people worldwide and imposes a considerable burden on patients and society due to its high prevalence and economic costs. The pathogenesis of OA is closely related to the progressive degradation of articular cartilage and the accompany inflammation; however, articular cartilage itself cannot heal and modulate the inflammation due to the lack of nerves, blood vessels, and lymph-vessels. Therefore, reliable and effective methods to treat OA remain highly desired.
View Article and Find Full Text PDFMultidisciplinary Effort Leading to Effective Tuberculosis Community Outbreak Containment in Israel.
Microorganisms
August 2024
Department of Tuberculosis and AIDS, Ministry of Health, Jerusalem 9438317, Israel.
Tuberculosis (TB) is the second-most prevalent cause of mortality resulting from infectious diseases worldwide. It is caused by bacteria belonging to the Mycobacterium tuberculosis complex (MTBC). In Israel, TB incidence is low, acknowledged by the WHO as being in a pre-elimination phase.
View Article and Find Full Text PDFThe making of the : human acclimatization to the Arctic environment and Soviet ideologies in Northern Medical Institutions.
Settl Colon Stud
October 2023
Department of Slavic and East European Languages and Cultures, The Ohio State University, Columbus, OH, USA.
This paper examines the history of the Soviet human acclimatization project in the North and Siberia, which spanned from medical experiments in Stalin's forced labor camps to the subsequent wave of industrialization in the region. The author argues that human acclimatization in the North was a settler colonial science project aimed at facilitating Russian administrators and engineers in asserting control over the territory and its resources, while creating a new homogeneous 'indigenous population' in Siberia and the North. This envisioned population, referred to as by the author, was intended to emerge through a two-way transformation: the adaptation of Indigenous peoples into Soviet ideologies and practices, and the acclimatization of settlers coming from the European part of the country to the Arctic environment.
View Article and Find Full Text PDFBreakthrough Measles among Vaccinated Adults Born during the Post-Soviet Transition Period in Mongolia.
Vaccines (Basel)
June 2024
Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Mongolia experienced a nationwide measles outbreak during 1 March 2015-31 December 2016, with 49,077 cases reported to the WHO; many were among vaccinated young adults, suggesting a possible role of vaccine failure. Advanced laboratory methods, coupled with detailed epidemiological investigations, can help classify cases as vaccine failure, failure to vaccinate, or both. In this report, we conducted a study of cases to identify risk factors for breakthrough infection for a subset of laboratory-confirmed measles cases.
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