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Antibodies directed against bacterial antigens in sera of Polish patients with primary biliary cholangitis.
Front Cell Infect Microbiol
January 2025
Clinic of Polish Gastroenterology Foundation, Warsaw, Poland.
Background: Primary biliary cholangitis (PBC) is a cholestatic, autoimmune liver disease with the presence of characteristic autoantibodies. The aim of the work was to determine the level of antibodies directed against bacterial antigens: (anti-anti), (anti-), (anti- ) and () in sera of PBC patients. We also performed studies on the impact of the bacterial peptides on the specific antigen-antibody binding.
View Article and Find Full Text PDFEvaluation of host immune responses to Mycobacteriophage Fionnbharth by route of delivery.
Virol J
January 2025
Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
For much of the last decade, tuberculosis (TB) was the leading cause of mortality due to an infectious pathogen (Mycobacterium tuberculosis, M.tb). Approximately 1.
View Article and Find Full Text PDFSerial intrauterine transfusion for severe fetal anemia due to anti-M alloimmunization.
Asian J Transfus Sci
September 2022
Department of Obstetrics and Gynecology, Faculty of Medicine Padjajaran University, Hasan Sadikin General Hospital, Bandung, Indonesia.
Anti-M antibody is one of the causes of severe fetal anemia and intrauterine death despite its relatively low frequency. A G3P2 26-year-old pregnant woman referred to our hospital at 29 weeks gestational age (WGA) with fetal hydrops. Her second pregnancy results in intrauterine fetal death at 35 WGA due to fetal hydrops.
View Article and Find Full Text PDFComparative analysis of improved m6A sequencing based on antibody optimization for low-input samples.
Sci Rep
January 2025
State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Suzhou Affiliated Hospital of Nanjing Medical University, Gusu School, Nanjing Medical University, Suzhou, 215002, China.
The most effective method for mapping N6-methyladenosine (mA) is mA RNA immunoprecipitation sequencing (MeRIP-seq). The quality of MeRIP-seq relies on various factors, with the anti-mA antibody being a crucial determinant. However, comprehensive research on anti-mA antibody selection and optimal concentrations for different tissues has been limited.
View Article and Find Full Text PDFAlloantibody Identification: The Importance of Temperature, Strength Reaction and Enzymes-A Practical Approach.
Hematol Rep
December 2024
Diagnostic Department, Immunohematology and Transfusion Medicine, Policlinico Riuniti, Via Pinto 1, 71122 Foggia, Italy.
Red blood cell (RBC) alloimmunization and antibodies formation against non-self antigens on red cells may occur after blood transfusion, pregnancies or other exposures. The RBC alloimmunization rate varies from 2% to 6% according to recent studies. The antibody screen is performed to identify or confirm the presence of antibodies in patient's serum or plasma, as a preoperative or pretransfusion test.
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