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Restoring Autophagy by Exercise Ameliorates Insulin Resistance Partly via Calcineurin-Driven TFEB Nuclear Translocation.
Clin Exp Pharmacol Physiol
March 2025
School of Physical Education, Hangzhou Normal University, Hangzhou, China.
Exercise activates autophagy and lysosome system in skeletal muscle, which are known to play an important role in metabolic adaptation. However, the mechanism of exercise-activated autophagy and lysosome system in obese insulin resistance remains covert. In this study, we investigated the role of exercise-induced activation of autophagy and lysosome system in improving glucose metabolism of skeletal muscle.
View Article and Find Full Text PDFEfficacy of Unsupervised YouTube Dance Exercise for Patients With Hypertension: Randomized Controlled Trial.
JMIR Cardio
January 2025
Department of General Medicine, Faculty of Medicine, Juntendo University, Tokyo, Japan.
Background: High blood pressure (BP) is linked to unhealthy lifestyles, and its treatment includes medications and exercise therapy. Many previous studies have evaluated the effects of exercise on BP improvement; however, exercise requires securing a location, time, and staff, which can be challenging in clinical settings. The antihypertensive effects of dance exercise for patients with hypertension have already been verified, and it has been found that adherence and dropout rates are better compared to other forms of exercise.
View Article and Find Full Text PDFThe Association of SLC16A1 (MCT1) Gene Polymorphism with Body Composition Changes during Weight Loss Interventions: A Randomized Trial with Sex-Dependent Analysis.
Appl Physiol Nutr Metab
January 2025
University of Cantabria, Department of Medical and Surgery Sciences, Santander, Cantabria, Spain.
Monocarboxylates, transported by monocarboxylate transporters (MCTs), have been proposed to influence energy homeostasis and exhibit altered metabolism during exercise. This study investigated the association between the Asp490Glu (T1470A) (rs1049434) polymorphism of the SLC16A1 (MCT1) gene and changes in body composition in males and females with overweight or obesity. The 173 participants (56.
View Article and Find Full Text PDFThe Influence of Resistance Training on Joint Flexibility in Healthy Adults: A Systematic Review, Meta-analysis, and Meta-regression.
J Strength Cond Res
December 2024
Department of Medicine, University of Padova, Via Giustiniani, Padova, Italy.
Favro, F, Roma, E, Gobbo, S, Bullo, V, Di Blasio, A, Cugusi, L, and Bergamin, M. The influence of resistance training on joint flexibility in healthy adults: A systematic review, meta-analysis, and meta-regression. J Strength Cond Res XX(X): 000-000, 2024-Joint flexibility is a key component of physical fitness.
View Article and Find Full Text PDFLoading Speed and Intensity in Eccentric Calf Training Impact Acute Changes in Achilles Tendon Thickness and Stiffness: A Randomized Crossover Trial.
Med Sci Sports Exerc
December 2024
Department of Rehabilitation Sciences, Ghent University, Ghent, BELGIUM.
Purpose: Eccentric calf training for Achilles tendinopathy shows variable success in athletes. Recent insights suggest a role for tendon fluid flow (exudation or redistribution) during exercise, which explains post-exercise reductions in thickness and increases in stiffness of the tendon. This fluid flow is thought to be beneficial as it may promote tendon remodeling, reduce intratendinous pressure, and alleviate pain.
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