Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Trends and outcomes in colorectal cancer surgery: a multicenter cross-sectional study of minimally invasive versus open techniques in Germany.
Surg Endosc
November 2024
Epidemiology, IQVIA, 60549, Frankfurt, Germany.
Background: The objective of this study was to assess the trend from open to modern minimally invasive (laparoscopic and robot-assisted) surgical techniques for colorectal cancer (CRC) in Germany, with a particular focus on hospital mortality, postoperative complications, and length of hospital stay.
Methods: A multicenter cross-sectional study was conducted using data from 36 German hospitals, encompassing 1,250,029 cases from January 2019 to December 2023. The study included all hospitalized patients aged ≥ 18 with CRC who underwent surgery.
2-(3-(Chloromethyl)benzoyloxy)benzoic Acid reduces prostaglandin E-2 concentration, NOX2 and NFKB expression, ROS production, and COX-2 expression in lipopolysaccharide-induced mice.
Prostaglandins Other Lipid Mediat
October 2024
Department of Anatomy, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Jalan Fauna No.2 Karangmalang, Yogyakarta 55281, Indonesia. Electronic address:
Article Synopsis
- - Inflammation is a key response to injury and infection, and while aspirin is commonly used for its anti-inflammatory effects, it has significant side effects, prompting the search for safer alternatives like the new compound 3-CHCl with a simpler, eco-friendly synthesis.
- - The study investigates the anti-inflammatory effects of 3-CHCl using a mouse model of inflammation induced by lipopolysaccharide (LPS), examining its impact on various inflammatory markers such as prostaglandin E-2 (PGE-2), NOX2, NFkB, reactive oxygen species (ROS), and COX-2.
- - Results showed that 3-CHCl significantly decreased levels of inflammatory markers and exhibited stronger anti-inflammatory
What are the real associations of homeostasis model assessment (HOMA) with body mass index and age?
Endokrynol Pol
September 2022
Clinic for Metabolic Assessment of Prof. MUDr. Karel Martiník, Hradec Králové, Czech Republic.
Introduction: Insulin resistance (IR), a key pathogenesis mechanism of metabolic disorders, can be tested using homeostatic model assessment (HOMA). HOMA-IR quantifies peripheral tissue IR, whereas HOMA-β determines insulin secretion. The cross-sectional study aimed to examine non-linear associations of HOMA indices with age when adjusting for body mass index (BMI), and thus to investigate the indices' ability to reflect the real development of glucose metabolism disorders over time.
View Article and Find Full Text PDFIdling for Decades: A European Study on Risk Factors Associated with the Delay Before a Narcolepsy Diagnosis.
Nat Sci Sleep
May 2022
Center for Sleep Medicine, Sleep Research and Epileptology, Klinik Barmelweid AG, Barmelweid, Aargau, Switzerland.
Purpose: Narcolepsy type-1 (NT1) is a rare chronic neurological sleep disorder with excessive daytime sleepiness (EDS) as usual first and cataplexy as pathognomonic symptom. Shortening the NT1 diagnostic delay is the key to reduce disease burden and related low quality of life. Here we investigated the changes of diagnostic delay over the diagnostic years (1990-2018) and the factors associated with the delay in Europe.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!