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Conducting Pairwise and Network Meta-analyses in Updated and Living Systematic Reviews: a Scoping Review Protocol.
JBI Evid Synth
January 2025
Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.
Objective: The objective of this scoping review will be to describe existing guidance documents or studies reporting on the conduct of meta-analyses in updated systematic reviews (USRs) or living systematic reviews (LSRs).
Introduction: The rapid increase in the medical literature poses a substantial challenge in keeping systematic reviews up to date. In LSRs, a review is updated with a pre-specified frequency or when some other signalling criterion is triggered.
Parent and Carer Experiences of Health Care Professionals' Communications About a Child's Higher Weight: a Qualitative Systematic Review.
JBI Evid Synth
January 2025
Health Sciences, Faculty of Social Sciences, Tampere University, Tampere, Finland.
Objective: The objective of this systematic review was to identify, critically appraise, and synthesize the best available qualitative evidence on parent and carer experiences of communications by health care professionals (HCPs) concerning children's higher weight.
Introduction: A child's higher weight can be a sensitive issue to discuss in health care, but successful communication with parents can increase parental compliance with treatment and improve overall family welfare. Public discourse on obesity has shifted in recent years and created pressure to change the way that weight is discussed in health care.
Mapping cells through time and space with moscot.
Nature
January 2025
Institute of Computational Biology, Helmholtz Center, Munich, Germany.
Single-cell genomic technologies enable the multimodal profiling of millions of cells across temporal and spatial dimensions. However, experimental limitations hinder the comprehensive measurement of cells under native temporal dynamics and in their native spatial tissue niche. Optimal transport has emerged as a powerful tool to address these constraints and has facilitated the recovery of the original cellular context.
View Article and Find Full Text PDFThe publication fate of abstracts awarded prizes at European Society of Paediatric Radiology annual scientific meetings.
Pediatr Radiol
January 2025
School of Medicine and Population Health, University of Sheffield, Sheffield, UK.
Background: The European Society of Paediatric Radiology (ESPR) awards prizes for outstanding work presented at their annual scientific meetings. The proportion of ESPR prize-winning abstracts to journal publications is not known. Contextualising abstract-to-publication proportions by evaluating publication experience can yield valuable insights and actionable outcomes to support researchers in overcoming barriers to journal publication.
View Article and Find Full Text PDFAnalysis of Research Waste in Phase III/IV Randomized Controlled Trials of Botulinum Toxin Type A.
Dermatol Surg
January 2025
All authors are affiliated with the Department of Plastic & Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Ninth People's Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: The application of randomized controlled trials (RCTs) outcomes of botulinum toxin type A (BoNT-A) to actual patient care faces a significant hurdle due to research waste (RW). This includes the results of RCTs that have not been published even 4 years after completion and those with insufficiently reported outcomes and design flaws. The prevalence of RW within BoNT-A-associated RCTs remains uncertain.
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