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MA -mediated lncRNA SCIRT stability promotes NSCLC progression through binding to SFPQ and activating the PI3K/Akt pathway.
Cell Mol Life Sci
January 2025
Department of Clinical Laboratory, Harbin Medical University Cancer Hospital, 150 Haping Road, Harbin, 150081, China.
Non-small cell lung cancer (NSCLC) has emerged as one of the most prevalent malignancies worldwide. N6-methyladenosine (mA) methylation, a pervasive epigenetic modification in long noncoding RNAs (lncRNAs), plays a crucial role in NSCLC progression. Here, we report that mA modification and the expression of the lncRNA stem cell inhibitory RNA transcript (SCIRT) was significantly upregulated in NSCLC tissues and cells.
View Article and Find Full Text PDFAdvancing healthcare through laboratory on a chip technology: Transforming microorganism identification and diagnostics.
World J Clin Cases
January 2025
Department of Basic Sciences, Biomedical Stomatology Research Group, Universidad de Antioquia U de A, Medellín 0057, Colombia.
In a recent case report in the , emphasized the crucial role of rapidly and accurately identifying pathogens to optimize patient treatment outcomes. Laboratory-on-a-chip (LOC) technology has emerged as a transformative tool in health care, offering rapid, sensitive, and specific identification of microorganisms. This editorial provides a comprehensive overview of LOC technology, highlighting its principles, advantages, applications, challenges, and future directions.
View Article and Find Full Text PDFUltrahigh Exchange Bias Field/Coercive Field Ratio in In Situ Formed Two-Dimensional Magnetic Te-CrO/CrTe Heterostructures.
Adv Mater
January 2025
Hunan Key Laboratory of Two-Dimensional Materials, State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan, 410082, China.
The exchange bias (EB) effect is a fundamental magnetic phenomenon, in which the exchange bias field/coercive field ratio (|H/H|) can improve the stability of spintronic devices. Two-dimensional (2D) magnetic heterostructures have the potential to construct low-power and high-density spintronic devices, while their typically air unstable and |H/H| lesser, limiting the possibility of applications. Here, 2D CrTe nanosheets have been systematically synthesized with an in situ formed ≈2 nm-thick Te doped CrO layer (Te-CrO) on the upper surface by chemical vapor deposition (CVD) method.
View Article and Find Full Text PDFBuilding a Culture of Health Through Leader-Inspired Nutrition.
Mil Med
January 2025
Consortium for Health and Military Performance, Department of Military and Emergency Medicine, F. Edward Hébert School of Medicine, Uniformed Services University, Bethesda, MD 20814, USA.
The balance of operational readiness and maintaining a healthy recruitment force presents increasing challenges within the DoD. Chronic preventable diseases, such as overweight and obesity, along with musculoskeletal injuries, are threats to recruitment and retention. Novel approaches are needed and leaders are in a unique position to serve a key role in influencing nutrition readiness.
View Article and Find Full Text PDFStandard operating procedure combined with comprehensive quality control system for multiple LC-MS platforms urinary proteomics.
Nat Commun
January 2025
School of Biological Science and Medical Engineering & School of Engineering Medicine, Beihang University, Beijing, China.
Urinary proteomics is emerging as a potent tool for detecting sensitive and non-invasive biomarkers. At present, the comparability of urinary proteomics data across diverse liquid chromatography-mass spectrometry (LC-MS) platforms remains an area that requires investigation. In this study, we conduct a comprehensive evaluation of urinary proteome across multiple LC-MS platforms.
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