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Atropine plus omeprazole for acute gastritis: Efficacy and safety analysis.
Pak J Pharm Sci
January 2025
Jian'ou Municipal Hospital, Nanping, Fujian, China.
Article Synopsis
- The article evaluates the effectiveness and safety of a combination treatment of atropine (ATR) and omeprazole (OME) for acute gastritis (AG) in comparison to anisodamine (ADM) with OME.
- The study involved 95 patients, with the ATR+OME group showing a higher success rate, fewer side effects, and quicker symptom relief than the ADM+OME group.
- Results indicated that the ATR+OME treatment significantly reduced inflammatory markers and gastrointestinal hormone levels, suggesting its strong efficacy and safety for managing AG, making it suitable for wider clinical use.
Understanding and Treating Laryngeal Mask Airway-Induced Intraoperative Hiccups.
Cureus
September 2024
Department of Anesthesiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
The laryngeal mask airway (LMA) has gained popularity as an airway management device in the perioperative setting due to its ease of use, reduced invasiveness compared to endotracheal intubation, and lower incidence of complications. However, hiccups, though relatively uncommon, can pose a significant challenge during the perioperative period when an LMA is in place. Abrupt movement because of hiccups can lead to delay in surgery as well as interfere with surgical instrumentation.
View Article and Find Full Text PDFA comprehensive study on the digestion, absorption, and metabolization of tropane alkaloids in human cell models.
J Hazard Mater
December 2024
Research Group "Analytical Chemistry of Contaminants", Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of International Excellence, ceiA3, E-04120 Almeria, Spain. Electronic address:
Tropane alkaloids (TAs) are toxic compounds with potent anticholinergic effects. Herbal infusions are among the most contaminated food commodities; however, the fate of TAs after ingestion remains poorly understood. This study presents a comprehensive investigation into the absorption, and metabolism of five TAs (atropine, scopolamine, tropine, homatropine, and apoatropine) following the digestion of contaminated tea.
View Article and Find Full Text PDFAtropine as an Adjunct in the Management of Pediatric Patients With Hypertrophic Pyloric Stenosis: A Single Institution Experience and Review of the Literature.
Cureus
July 2024
Department of Pediatric Surgery, Hackensack Meridian Health Jersey Shore University Medical Center, Neptune, USA.
Article Synopsis
- Infantile hypertrophic pyloric stenosis (IHPS) is a condition in infants characterized by a thickened pyloric muscle that causes gastric outlet obstruction, typically manifesting as non-bilious projectile vomiting within the first few weeks of life.
- The standard treatment is a surgical procedure called pyloromyotomy, but for some patients unable to undergo surgery or those experiencing recurring issues post-surgery, atropine can be an alternative option.
- In a small study of five pediatric patients treated with atropine, three showed successful symptom resolution, while two required surgery; the findings suggest that atropine is a safe and potentially effective alternative treatment for IHPS.
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