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Background: Intrahepatic cholangiocarcinoma (ICC) presents a significant clinical challenge due to its high fatality rate and limited surgical candidacy. With only 30-40% of patients eligible for surgery upon diagnosis, alternative therapies are imperative. This study assesses the efficacy of Yttrium-90 (Y-90) radioembolization for unresectable ICC patients in a non-university tertiary care center (NUTCC).
View Article and Find Full Text PDFDifferentiating true precocious puberty and puberty variants in consecutive 275 girls: a single center experience.
J Pediatr Endocrinol Metab
January 2025
Department of Pediatric Endocrinology, Kocaeli City Hospital, Kocaeli, Türkiye.
Objectives: This study aimed to identify clinical features of girls referred to a pediatric endocrinology clinic for suspected precocious puberty, differentiate true precocious puberty from other variants, evaluate treatment status, and identify distinguishing factors between patient groups.
Methods: We retrospectively evaluated the records of 275 consecutive girls aged 0-10 years referred for suspected precocious puberty.
Results: Among the patients, 30 (10.
Staged versus Simultaneous Surgery for Adult Spinal Deformity - A Systematic Review and Meta-analysis.
Spine (Phila Pa 1976)
January 2025
Department of Orthopaedics, All India Institute of Medical Sciences, Rishikesh, India.
Study Design: Systematic review and meta analysis.
Objective: To assess the safety and efficacy of staged versus same-day spinal fusion surgeries in Adult spinal deformity (ASD).
Background: ASD surgeries are associated with high complication rates, ranging from 10% to 40%.
The Correlation Between Gender, Age, Curvature, and Symptom-related Changes in C6 and C7 Slope in 10,000 Subjects.
Spine (Phila Pa 1976)
January 2025
school of Life Sciences, Beijing University of Chinese Medicine, Beijing, P.R. China.
Study Design: A cross-sectional analysis of 10,000 cervical spine X-rays.
Objective: This study investigates the variations in C6S and C7S across demographic factors (gender, age, cervical curvature, symptoms) and explores their correlation. Additionally, machine learning models are applied to improve the accuracy of C7S prediction.
Defining Substantial Clinical Benefits of PROMIS Pain Interference and Physical Function in Patients Undergoing Lumbar and Thoracolumbar Spine Surgery.
Spine (Phila Pa 1976)
January 2025
Department of Neurological Surgery, Washington University, St. Louis, MO, USA.
Study Design: Prospective cohort study.
Objective: This study aims to define Substantial Clinical Benefit (SCB) thresholds for PROMIS physical function (PF) and pain interference (PI) in lumbar or thoracolumbar spine surgery population.
Summary Of Background Data: Patient-reported outcome measures (PROMs) are widely used in spine surgery to assess treatment efficacy.
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