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Adjuvant Chemotherapy With UFT/LV UFT/LV Plus PSK in Stage II/III Colorectal Cancer.
Anticancer Res
February 2024
Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University Graduate School of Medicine, Maebashi, Japan.
Background/aim: Uracil-tegafur+leucovorin (UFT/LV), an oral adjuvant therapy for stage II/III colorectal cancer, is non-inferior to standard weekly fluorouracil and folinate. Although polysaccharide K (PSK) has been evaluated as a postoperative adjuvant colorectal cancer drug, its efficacy remains unclear. This randomized phase II trial compared UFT/LV+PSK with UFT/LV as adjuvant chemotherapy.
View Article and Find Full Text PDFLong-term oncological outcomes of robotic versus laparoscopic gastrectomy for gastric cancer: multicentre cohort study.
Br J Surg
January 2024
Department of General Surgery, Centre for Minimally Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
Background: The aim of this multicentre cohort study was to compare the long-term oncological outcomes of robotic gastrectomy (RG) and laparoscopic gastrectomy (LG) for patients with gastric cancer.
Methods: Patients with gastric cancer who underwent radical gastrectomy by robotic or laparoscopic approaches from 1 March 2010 to 31 December 2018 at 10 high-volume centres in China were selected from institutional databases. Patients receiving RG were matched 1 : 1 by propensity score with patients undergoing LG.
Minimally invasive liver resection for cholangiolocellular carcinoma: A single-institution experience.
Asian J Endosc Surg
January 2024
Department of Surgery, Kansai Rosai Hospital, Amagasaki, Hyogo, Japan.
Article Synopsis
- Cholangiolocellular carcinoma (CoCC) is often misdiagnosed due to its similarities with cholangiocellular carcinoma (CCC), making preoperative identification challenging.
- A study of 15 CoCC patients treated with either laparoscopic liver resection (LLR) or open liver resection (OLR) showed varying outcomes, with a significant number achieving good 5-year disease-free and overall survival rates.
- The study suggests that minimally invasive liver resection is a safe and effective treatment option for CoCC, but further research is required to validate these findings.
Eyelid Necrosis and Secondary Cicatrical Ectropion Secondary to Levamisole-Associated Vasculitis.
Ophthalmic Plast Reconstr Surg
September 2017
Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A.
A 56-year-old female presented with eyelid necrosis secondary to systemic levamisole-induced vasculitis. Skin biopsy revealed necrotic epidermis with small-vessel thrombosis, fibrinoid reaction, and neutrophilic infiltration of vessel walls in the dermis with +pANCA. She was treated with plasmapheresis and steroids.
View Article and Find Full Text PDFLong-term survival benefits of adjuvant chemotherapy by decreasing incidence of tumor recurrence without delaying relapse in stage III colorectal cancer.
Int J Colorectal Dis
October 2011
Division of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan.
Backgrounds And Aims: To elucidate the survival benefits of adjuvant chemotherapy by decreasing incidence or by delaying time of tumor recurrence, we reported the long-term results of a nonrandomized prospective study comparing the adjuvant chemotherapy to no chemotherapy in stage III colorectal cancer.
Patients: From 1991 to 1995, 463 patients with stage III colorectal cancer were divided to three groups which were no chemotherapy, weekly chemotherapy, and monthly chemotherapy (5-FU plus levamisole).
Results: The recurrent incidence was significantly decreased in patients with chemotherapy (47.
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