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Prevalence of peripheral neuropathy in children with transfusion-dependent thalassemia: A hospital-based cross-sectional study.
J Family Med Prim Care
December 2024
Department of Pediatrics, Lady Hardinge Medical College, New Delhi, India.
Background: Our study aimed to determine the prevalence of Peripheral Neuropathy (using nerve conduction studies (NCS)) in children with transfusion-dependent thalassemia aged between 5 to 18 years and to study its correlation with chronic anemia, ferritin levels, chelation status, annual transfusion requirement, deficiency of serum Vitamin B12, and Folate levels.
Methods: In this hospital-based cross-sectional study, 100 eligible children were enrolled in a tertiary care teaching hospital in New Delhi, India. Neurological examinations focusing on peripheral neuropathy followed by NCS were performed on all the patients.
Bariatric surgery and HIV: Joint venture between family, primary care, and HIV physicians.
J Family Med Prim Care
December 2024
Department of HIV and Blood Borne Viruses, Milton Keynes University Hospital, NHS Foundation Trust, Milton Keynes, UK.
We report a case of a 49-year-old female with a history of HIV infection for 12 years. The patient had excellent compliance with antiretroviral medications, raltegravir 400 mg twice daily and truvada once daily for HIV. Over the years, she maintained an undetectable viral load with a CD4+ count >200 cells/μL.
View Article and Find Full Text PDFComparison of single-point insulin sensitivity estimator (SPISE) index and cognitive performance in vitamin B-deficient young adults: An analytical cross-sectional study.
J Family Med Prim Care
December 2024
PhD Scholar, Department of Biochemistry, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Chennai, Tamil Nadu, India.
Background: Vitamin B is an essential micronutrient, aids in synthesis of neurotransmitters, and vital for cognitive function. In the current younger population with more of electronic gadgets and scientific world seems to slow down critical thinking and impairs the trick of comprehensive subjective learning. Vitamin B deficiency has been linked to insulin-resistant state and future cardiovascular risk.
View Article and Find Full Text PDFBackground: Identifying individuals' levels of tau PET pathology could prove to be beneficial in clinical settings, given that emerging therapies aimed reducing Aβ seem to be most effective in these individuals. Here, we present the cases of four patients who visited the memory clinic at the University of Pittsburgh Medical Center between June and December 2023 and underwent both Aβ and tau-PET scans.
Method: These individuals had standard clinical and cognitive outcomes, typical blood tests order in patients with memory impairment, MRI, and, as part of the HEAD study, PET PIB Aβ and two tau PET tracers (MK6240 and Flortaucipir).
Public Health.
Alzheimers Dement
December 2024
University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Background: By 2060, an estimated 3.5 million Latinos may develop Alzheimer's disease (AD). Lifestyle factors, such as adhering to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, may improve cognition and reduce AD risk.
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