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Vaccine
September 2024
National Coordinator of the Working Group "Vaccines and Immunization Policies", Italian Society of Hygiene, Preventive Medicine and Public Health, Italy.
J Pediatr
September 2016
Department of Pediatric and Public Health Sciences, University of Torino, Torino, Italy.
Objective: To compare tumor risk in the 4 Beckwith-Wiedemann syndrome (BWS) molecular subgroups: Imprinting Control Region 1 Gain of Methylation (ICR1-GoM), Imprinting Control Region 2 Loss of Methylation (ICR2-LoM), Chromosome 11p15 Paternal Uniparental Disomy (UPD), and Cyclin-Dependent Kinase Inhibitor 1C gene (CDKN1C) mutation.
Study Design: Studies on BWS and tumor development published between 2000 and 2015 providing (epi)genotype-cancer correlations with histotype data were reviewed and meta-analysed with cancer histotypes as measured outcome and (epi)genotype as exposure.
Results: A total of 1370 patients with BWS were included: 102 developed neoplasms (7.
G Batteriol Virol Immunol Ann Osp Maria Vittor Torino
December 1996
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