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Sci Rep
January 2025
Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt.
Yttrium oxide nanoparticles (YONPs) have emerged as a promising avenue for cancer therapy, primarily due to their distinctive properties that facilitate selective targeting of cancer cells. Despite their potential, the therapeutic effects of YONPs on human epidermoid skin cancer remain largely unexplored. This study was thus conducted to investigate the impact of YONPs on both human skin normal and cancer cells, with an emphasis on assessing their cytotoxicity, genotoxicity, and the mechanisms underlying these effects.
View Article and Find Full Text PDFAnal Chim Acta
January 2025
State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, 130000, PR China. Electronic address:
Nitrite is widely used as a food additive, and it is of great significance to realize accurate detection of nitrite for food safety. Electrochemical technique is characterized by simple operation and portability, which enables rapid and accurate detection. The key factors affecting the nitrite detection performance are the electrocatalytic activity and interfacial electron transfer efficiency of the electrode.
View Article and Find Full Text PDFEnviron Res
January 2025
Tianjin Key Laboratory of Pulp and Paper, Tianjin University of Science and Technology, Tianjin 300457, P.R. China.
Herein, a biochar-supported zero-valent iron (ZVI) nanosheet catalyst (Fe@BC) for the activation of persulfate to degrade ciprofloxacin (CIP) was prepared using industrial kraft lignin and Fenton sludge as carbon and iron sources, respectively. Fe@BC showed considerably better CIP degradation efficiency (96.9% at 20 mg·L) than traditional catalysts.
View Article and Find Full Text PDFWater Res
January 2025
School of Civil and Environmental Engineering, University of New South Wales, Sydney, NSW 2052, Australia. Electronic address:
Chlorine, the most widely utilized disinfectant for drinking water globally, has recently been implicated in facilitating the spread of antibiotic resistance genes (ARGs), raising concerns about its underestimated environmental and ecological risks. However, given the current fragmented research focus and results, a comprehensive understanding of the potential mechanisms and influencing factors behind chlorination-promoted ARGs transmission in drinking water systems is crucial. This work is the first to systematically review the variations in abundance, transmission mechanisms, influencing factors, and mitigation strategies related to ARGs during the chlorination process.
View Article and Find Full Text PDFCell Commun Signal
January 2025
Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Road, Lu Zhou, Luzhou, Sichuan, 646000, China.
This review comprehensively explores the critical role of calcium as an essential small-molecule biomessenger in skeletal muscle function. Calcium is vital for both regulating muscle excitation-contraction coupling and for the development, maintenance, and regeneration of muscle cells. The orchestrated release of calcium from the endoplasmic reticulum (ER) is mediated by receptors such as the ryanodine receptor (RYR) and inositol 1,4,5-trisphosphate receptor (IP3R), which is crucial for skeletal muscle contraction.
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