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Introduction: The threat posed by tuberculosis persists in developing countries. Individuals under the age of five were more likely to develop central nervous system (CNS) tuberculosis. CNS Tuberculoma of the posterior fossa has rarely been reported, and its consequences are more devastating due to the limited space of the posterior fossa.

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Disseminated central nervous system tuberculoma in a patient with scrub typhus: A case report.

Exp Ther Med

June 2024

Department of Neurology, The Affiliated Changsha Central Hospital, University of South China, Changsha, Hunan 410000, P.R. China.

Article Synopsis
  • A 60-year-old man initially diagnosed with scrub typhus experienced symptoms like fever and muscle soreness, improved with doxycycline, but later showed signs of CNS tuberculosis.
  • Tests confirmed Mycobacterium tuberculosis in his cerebrospinal fluid, and brain imaging revealed lesions, leading to a diagnosis of CNS tuberculoma and effective treatment with anti-tuberculosis therapy.
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Intracranial tuberculomas: review of MRI findings and clinical features.

Clin Radiol

May 2024

Pelita Harapan University, Faculty of Medicine, Tangerang, Indonesia; Department of Radiology, Siloam Hospital Lippo Village, Tangerang, Indonesia.

Aim: To present a comprehensive analysis of the clinical features and magnetic resonance imaging (MRI) findings of intracranial tuberculomas in Indonesia.

Materials And Methods: This was a retrospective analysis of brain MRI from 58 patients (29 women), mean age ± SD = 39 ± 2 years, diagnosed with intracranial tuberculomas. Clinical data, including symptoms, cerebrospinal fluid examination results, and MRI were also analysed.

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Introduction: There is evidence showing that central nervous system TB (CNS-TB) causes meningitis, pachymeningitis, tuberculomas, and granulomas. However, the impact of pulmonary or spine TB on brain morphology and thickness is yet to be documented. TB is associated with increased levels of inflammatory biomarkers in specific brain regions.

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Article Synopsis
  • * A case of a 13-year-old girl with severe neurological symptoms revealed a cerebellar lesion, which was diagnosed as a tuberculoma after surgical intervention and histological analysis, ultimately leading to successful treatment with anti-TB medication.
  • * Despite being rare, CNS tuberculomas should be considered in patients from TB-endemic regions presenting with symptoms of intracranial masses, even in those
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