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Genetic alteration analysis of non-pediatric diffuse midline glioma, H3 K27-altered.
Hum Pathol
December 2024
Department of Pathology, Seoul National University Bundang Hospital, 173-82 Gumi-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-707, Republic of Korea; Department of Pathology, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea. Electronic address:
Diffuse midline gliomas with H3 K27-alteration (DMGH3) are lethal and inoperable brain tumors. Although DMGH3s mainly occur in pediatric patients, they have also occurred in adult patients. This study aimed to analyze the clinicopathological significance of targetable genetic alterations in non-pediatric DMGH3.
View Article and Find Full Text PDFPancreaticoduodenal Artery Aneurysm in a Patient with Celiac Artery Atresia.
Ann Vasc Surg
November 2024
Division of Vascular and Endovascular Surgery, St. Elizabeth's Medical Center, Boston University School of Medicine, Boston, MA. Electronic address:
Article Synopsis
- - A case study outlines the treatment of a rare pancreaticoduodenal artery aneurysm (PDAA) in a 60-year-old woman with a unique anatomy—she had a hypoplastic celiac artery and blood supply coming from a dilated superior mesenteric artery.
- - The patient underwent open surgical reconstruction, which involved resecting the PDAA and reconstructing the pancreaticoduodenal artery, leading to successful blood flow restoration during and after surgery.
- - The surgical intervention was effective; the patient recovered well and was discharged five days post-op with normal liver function tests, indicating a promising management strategy for similar cases.
Compact Arterial Monitoring Device Use in Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): A Simple Validation Study in Swine.
Cureus
October 2024
Department of Anesthesiology, Uniformed Services University of the Health Sciences, Bethesda, USA.
Article Synopsis
- - Hemorrhage is the main cause of preventable death in trauma situations, leading to military and civilian advancements in medical practices, particularly through the use of tourniquets to manage extremity bleeding and save lives.
- - While tourniquets have significantly decreased deaths from bleeding in military settings, noncompressible hemorrhage still poses a major risk, especially before patients receive definitive medical care.
- - The study explores using a small, disposable pressure monitor during resuscitative endovascular balloon occlusion of the aorta (REBOA) to enhance blood pressure monitoring, facilitate better resuscitation practices, and reduce the need for blood products in extreme environments.
Orotracheal Intubation Challenges in an Anticipated Difficult Mask Ventilation, Preoxygenation, Tricky Laryngoscopy, and Supraglottic Airway Device Insertion: A Case Report.
Cureus
September 2024
Anaesthesiology, Critical Care, and Pain Medicine, All India Institute of Medical Sciences, Guwahati, Assam, IND.
With the advancement of technology, equipment, and airway management knowledge, anticipated difficult airway (DA) management has come a long way towards excellence. Usually, anticipated difficulties are related to bag-mask ventilation (BMV), laryngoscopy, intubation, or supraglottic airway placement; all in a single patient pose exceptionally challenging airway management. We may electively plan a surgical airway, but the option may not be available, especially when the patient provides tracheostomy permission only for emergency airway management, not for an elective.
View Article and Find Full Text PDFAscites production and prognosis after ventriculoperitoneal shunt for diffuse midline gliomas in children: A case series.
Medicine (Baltimore)
October 2024
Department of Clinical Laboratory, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
Rationale: DMG is a highly invasive and lethal type of brain tumor. As these tumors progress, they often compromise the CSF circulation, leading to hydrocephalus. Ventriculoperitoneal shunt (VPS) is commonly employed to manage hydrocephalus; however, the complication of VPS-induced ascites, particularly in the presence of tumor cells, is a significant concern that merits attention.
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