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Atomoxetine-Induced Pheochromocytoma and Paraganglioma Crisis Managed With Veno-Arterial Extracorporeal Membrane Oxygenation.
Cureus
November 2024
Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, JPN.
Pheochromocytoma and paragangliomas (PPGLs) crises can be triggered by various factors, including norepinephrine reuptake inhibitors used to treat attention deficit hyperactivity disorder (ADHD), which worsen symptoms in patients with PPGLs. Therefore, attention should be paid to the potential for serious adverse reactions in patients with PPGLs taking ADHD medications. A 21-year-old man presented to the emergency department with acute onset of severe respiratory and circulatory failure after initiating atomoxetine treatment.
View Article and Find Full Text PDFManagement Strategies for Hypertensive Crisis: A Systematic Review.
Cureus
August 2024
Medicine, Najran University, Najran, SAU.
A hypertensive crisis is defined as a sudden and significant rise in blood pressure. The blood pressure reading is 180/120 mmHg or higher. A hypertensive crisis is a medical emergency.
View Article and Find Full Text PDFNaphazoline intoxication managed with minimally invasive cardiac output monitoring.
Am J Emerg Med
March 2024
Department of Emergency and Critical Care Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan. Electronic address:
Article Synopsis
- * The patient showed severe symptoms related to naphazoline intoxication, including bradycardia and high blood pressure, prompting treatment with phentolamine and nicardipine under careful monitoring of systemic vascular resistance.
- * Successful treatment led to normalization of vascular resistance and the patient was discharged after four days, indicating the effectiveness of using advanced monitoring systems to manage such cases.
Octopamine is involved in TRP-induced thermopreference responses in American cockroach.
J Insect Physiol
January 2024
Department of Animal Physiology and Neurobiology, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Poland.
Insects' thermoregulatory processes depend on thermosensation and further processing of thermal information in the nervous system. It is commonly known that thermosensation involves thermoreceptors, including members of the TRP receptor family, but the involvement of neurotransmitters in thermoregulatory pathways remains unstudied. We conducted test to determine whether octopamine, a biogenic amine that acts as a neurotransmitter and neurohormone in insects, is involved in TRP-induced thermoregulatory responses in Periplaneta americana.
View Article and Find Full Text PDFPeptiligase, an enzyme for efficient chemo-enzymatic synthesis of aviptadil.
Int J Biol Macromol
December 2023
Bioprocess Engineering Department, Institute of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Increasing attention to peptides as prospective therapeutics has created a renaissance in searching for new alternatives to the current peptide synthetic approaches as well as their modification. In this context, it is necessary to develop different approaches for peptide ligation. Using enzymes as a novel strategy and powerful tool for the peptide and protein ligation has recently received a lot of attention.
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