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Unlabelled: One of the principles of prevention and non-drug treatment of liver diseases, including hepatitis of various etiologies, is the normalization of the diet, including the use of daily diet foods with physiologically active ingredients, in particular betulin, which helps to reduce metabolic and oxidative processes within liver cells. The aim of the work was to evaluate the in vivo effect of triterpene alcohol betulin Roth isolated from the bark of birch Betula pendula Roth. added to fat-containing products (for example, mayonnaise) on the biochemical parameters of blood and the morphological structure of the liver of rats with initiated acute toxic hepatitis.
View Article and Find Full Text PDFHost size overrides maternal effects on the development of a secondary hyperparasitoid wasp.
J Insect Sci
January 2025
Department of Terrestrial Ecology, Netherlands Institute of Ecology, Wageningen, The Netherlands.
Unraveling the numerous factors that drive phenotypic variation in trait expression among animals has long presented a significant challenge. Whereas traits like growth and adult size are often heritable and are passed on from one generation to the next, these can be significantly affected by the quality and quantity of resources provided by one or both parents to their offspring. In many vertebrates, such as birds and mammals, parents raise their young until adult, providing food, shelter, and protection.
View Article and Find Full Text PDFOptimizing Recovery Strategies in Elite Speedskating: A Comparative Analysis of Different Modalities.
J Funct Morphol Kinesiol
January 2025
3rd Department of Internal Medicine and Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
As short-track speed skaters have to race multiple races to achieve success during competition, optimizing the recovery between efforts is a noteworthy performance determinant. Therefore, we compared three different recovery modalities (active cycling recovery, pneumatic compression boots, and isocapnic breathing protocol) in the context of perceived subjective pain and recovery variables, multiple biochemical and biomechanical indices, CMJ height and power, as well as repeated efforts on the ice track. Fifteen elite short-track speed skaters (eight males and seven females; age 18.
View Article and Find Full Text PDFHRAMS Proteomics Insights on the Anti-Filarial Effect of : Implications in Phytochemical-Based Drug-Targeting and Designing.
Proteomes
December 2024
Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi 221005, India.
Lymphatic filariasis (LF) continues to impact 657 million individuals worldwide, resulting in lifelong and chronic impairment. The prevalent anti-filarial medications-DEC, albendazole, and ivermectin-exhibit limited adulticidal efficacy. Despite ongoing LF eradication programs, novel therapeutic strategies are essential for effective control.
View Article and Find Full Text PDFDevelopment, Validation, and Application of the Paya Hamsan Technologies Underivatized Newborn Screening Assay (PHUNSA) for Inborn Metabolic Disorders in Dried Blood Spot Samples from Iranian Infants.
Int J Neonatal Screen
January 2025
Molecular Engineering & Sciences Institute, Arak University, Arak 3848177584, Iran.
Screening for inborn metabolic disorders (IMDs) in newborns is an important way to prevent serious metabolic and developmental difficulties that can result in lasting disabilities or even death. Electrospray ionization tandem mass spectrometry (MS/MS) provides an efficacious newborn blood spot screening (NBS) mechanism for analyzing dried blood spot specimens (DBSs) for biochemical markers for these conditions. Where possible, the elimination of derivatization in specimen preparation can simplify and streamline analysis.
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