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  • * It emphasizes that extra pulmonary tuberculosis can present in unusual ways, which might lead to misdiagnosis if not considered in the differential diagnosis, especially in the bones of the limbs.
  • * The report highlights the need for vigilance among clinicians, as conditions like Enchondromatosis or Chronic pyogenic osteomyelitis can resemble this rare presentation, despite a significant decrease in such cases due to advances in anti-tubercular therapy.
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Tropheryma whipplei in the stool samples of children with acute diarrhea: a study from Tehran, Iran.

BMC Infect Dis

February 2022

National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, Kabudar Ahang, Hamadan, Iran.

Background: Recently, Tropheryma whipplei has been suggested as one of the causative agents of diarrhea among children worldwide. Limited data is available on the prevalence of T. whipplei among children with diarrhea in most countries such as Iran.

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Article Synopsis
  • Actinomycosis is a rare head and neck infection in children, often linked to chronic conditions, presenting symptoms like swelling and abscesses, and can lead to serious complications like osteomyelitis.!* -
  • Two pediatric cases of actinomycosis stemming from congenital lesions were analyzed, which included surgical removal of affected areas and long-term antibiotic treatment, contributing to a total of 34 reviewed cases in the literature with a median age of 7.5 years.!* -
  • The study emphasizes the need to consider actinomycosis in cases of chronic sinus drainage in the head and neck, suggests using MR imaging to check for complications, and highlights the effectiveness of penicillin-based antibiotics along with surgery
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Actinomycosis is a relatively uncommon bacterial disease of childhood, especially when presenting as deep-seated infections. Only 10% of affected patients are younger than 18 years of age. In children, cervical actinomycosis is the most common form of clinical presentation, and among the abdominopelvic form, renal abscesses are rare.

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Aim: To obtain the first molecular epidemiological survey of Tropheryma whipplei intestinal colonization in Italy. Materials & methods: Retrospective, observational study to assess the prevalence of T. whipplei, the causative agent of Whipple's disease, in stool samples (real-time PCR) of patients attending the Center for Tropical Diseases (Italy) and risk factors associated.

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