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[Importance of E-cadherin; expression in the inmunohistochemical diagnosis of breast cancer].
Invest Clin
December 2006
Laboratorio de Patología Molecular NOVAPATH, Maracaibo, Venczuela.
It has been propossed that 50% of lobular carcinomas (LC) may change their phenotype to ductal carcinoma (DC) in 20 years. Since the prognosis and treatment of both breast carcinomas is different, it seems to be important; investigate through immunohistochemistry the loss of E-cadherin expression. E-cadherin expression was investigated in 90 cases with diagnosis or histological appearance of LC or mixed carcinomas (MxC), and in 30 DC selected among 385 cases received during year 2005 to be examined for immunohistochemical diagnosis.
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