Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0002-9149(79)90274-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antihypertensive effects and changes in extracellular water content by mineralocorticoid receptor antagonists in patients with primary aldosteronism.
Hypertens Res
November 2024
Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University, Yufu, Japan.
In primary aldosteronism (PA), non-suppressible excessive aldosterone secretion due to dietary salt intake significantly contributes to hypertension and cardiovascular complications. Blocking the overactivation of mineralocorticoid receptors (MRs) with mineralocorticoid receptor antagonists (MRAs) is a cornerstone for the medical treatment of PA. However, the role of MRAs in controlling hypertension remains unclear.
View Article and Find Full Text PDFPrevalence of cardiomyopathy and cardiac mortality in a colony of non-purebred cats in New Zealand.
N Z Vet J
January 2025
Tāwharau Ora - School of Veterinary Science, Massey University, Palmerston North, New Zealand.
Article Synopsis
- The study aimed to assess the occurrence of subclinical cardiomyopathy and cardiac-related deaths in a colony of non-purebred cats in New Zealand as a representation of the general cat population.
- A total of 132 cats underwent physical exams and echocardiography, revealing that 18.2% had heart disease, primarily hypertrophic cardiomyopathy (HCM), while 24% exhibited heart murmurs.
- Over a ten-year period, heart disease was determined to be the cause of death in 5.3% of the cat population studied, with a specific prevalence of HCM-related deaths at 3.8%.*
Cellular calcium handling and electrophysiology are modulated by chronic physiological pacing in human induced pluripotent stem cell-derived cardiomyocytes.
Am J Physiol Heart Circ Physiol
November 2024
Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Electric pacing of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) has been increasingly used to simulate cardiac arrhythmias in vitro and to enhance cardiomyocyte maturity. However, the impact of electric pacing on cellular electrophysiology and Ca handling in differentiated hiPSC-CM is less characterized. Here we studied the effects of electric pacing for 24 h or 7 days at a physiological rate of 60 beats/min on cellular electrophysiology and Ca cycling in late-stage, differentiated hiPSC-CM (>90% troponin, >60 days postdifferentiation).
View Article and Find Full Text PDFCardiac remodeling: novel pathophysiological mechanisms and therapeutic strategies.
J Biochem
September 2024
Division of Cardiocirculatory Signaling, National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.
Article Synopsis
- The text discusses the ongoing challenges in treating heart failure, specifically highlighting that many patients do not respond to current heart failure medications despite advancements in the field.
- It focuses on a specific type of heart failure called heart failure with preserved ejection fraction (HFpEF), which is characterized by preserved heart pumping ability but poor relaxation and diastolic function, often linked to metabolic issues and high-fat diets.
- The review suggests that mitochondrial dysfunction plays a key role in heart failure progression, proposing a new treatment strategy targeting mitochondrial health and redox balance to improve outcomes for patients.
Meta-analysis of the intervention effects of tai chi on fasting blood glucose, blood pressure and triglyceride in middle-aged and elderly people.
Aging Male
December 2024
Department of Sports Science, Kyonggi University, Suwon, South Korea.
Background: Hypertension, hyperlipidemia, and hyperglycemia have emerged as global health concerns of paramount significance. With the burgeoning popularity of mind-body therapy, cardiovascular patients have increasingly exhibited a vested interest in the practice of Tai Chi. The objective of this study seeks to quantitatively assess the impact of Tai Chi interventions on blood pressure, lipid levels, and glucose concentrations among the elderly population, thereby explaining the optimal intervention protocol.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!