Estriol serum levels, neonatal vitality and stromal villous edema were studied in diabetic pregnancies. The average serum estriol levels in diabetic patients whose placentas had villous edema was 26.45 +/- 9.16 ng/ml. This value was significantly lower than that of the diabetic patients without villous edema (59.26 +/- 12.06 ng/ml). The average serum estriol levels in diabetic patients who gave birth to depressed newborns was 25.68 +/- 9.73 ng/ml. In diabetic women who gave birth to vigorous newborns this value was 56.57 +/- 14.10 ng/ml. The difference was statistically significant. These results and similar findings from other authors are discussed.
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