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Astragaloside IV attenuates cadmium induced nephrotoxicity in rats by activating Nrf2.
Sci Rep
January 2025
Department of Nephrology, the Key Laboratory for the Prevention and Treatment of Chronic Kidney Disease of Chongqing, Chongqing Clinical Research Center of Kidney and Urology Diseases, Xinqiao Hospital, Army Medical University, (Third Military Medical University), Chongqing, China.
Acute kidney injury (AKI) has become a disease of global concern due to its high morbidity and mortality. This has highlighted the need for renoprotective agents. Astragaloside IV (AS-IV) is a saponin isolated from Astragalus membranaceus with good antioxidant, anti-inflammatory and anti-tumor properties.
View Article and Find Full Text PDFInhibitory effects of cadmium and hydrophilic cadmium telluride quantum dots on the white rot fungus .
Heliyon
January 2025
Department of Microbiology (Biocenter 1, Viikinkaari 9), Faculty of Agriculture and Forestry, University of Helsinki, Finland.
The white rot fungus was investigated for its ability to decolorize the reactive textile dye Reactive Black 5 (RB5) that was co-exposed to CdCl and quantum dots (QDs) consisting of a CdTe core capped with two different hydrophilic organic ligands (NAC and MPA). Without co-exposure, completely decolorizes RB5 within 9 days. The highest inhibitory effect was found for soluble CdCl with an EC of 583 μg l, followed by MPA-QDs (10,628 μg l) and NAC-QDs (17,575 μg l).
View Article and Find Full Text PDFHardness-Dependent Freshwater Quality Criteria for the Protection of Aquatic Organisms for Cadmium in China.
Toxics
December 2024
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.
Cadmium poses a significant threat to freshwater aquatic organisms and ecosystems, making it essential to establish regional freshwater quality criteria (FWQC) in China to safeguard these organisms. The toxicity database for cadmium covered 249 acute toxicity data from 52 species (seven phyla and 27 families) and 62 chronic toxicity data from 21 species (four phyla and 12 families). During short-term exposure, displayed the most sensitivity to cadmium, whereas showed the most sensitivity in long-term exposure scenarios.
View Article and Find Full Text PDFExploring the combined toxicity of boron nitride nanosheets, cadmium and natural organic matter on Daphnia magna.
Aquat Toxicol
December 2024
Brazilian Nanotechnology National Laboratory (LNNano), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Sao Paulo, Brazil. Electronic address:
The increase in anthropogenic activities has led to the release of numerous chemicals and pollutants into aquatic ecosystems, raising significant concerns for water quality and health. Among the emerging issues is the interaction between pollutants and nanomaterials (mixture effects). In this work, it was studied the combined toxicity of boron nitride nanosheets (BNNS) and cadmium (Cd) incorporating the influence of natural organic matter (NOM) to enhance ecological relevance for the first time.
View Article and Find Full Text PDFInteractive effects of temperature, cadmium, and hypoxia on rainbow trout (Oncorhynchus mykiss) liver mitochondrial bioenergetics.
Ecotoxicol Environ Saf
January 2025
Department of Biomedical Sciences, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada. Electronic address:
Fish in their natural environments possess elaborate mechanisms that regulate physiological function to mitigate the adverse effects of multiple environmental stressors such as temperature, metals, and hypoxia. We investigated how warm acclimation affects mitochondrial responses to Cd, hypoxia, and acute temperature shifts (heat shock and cold snap) in rainbow trout. We observed that state 3 respiration driven by complex I (CI) was resistant to the stressors while warm acclimation and Cd reduced complex I +II (CI + II) driven state 3 respiration.
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