Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0002-9394(74)90396-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pleomorphic Sarcoma, an Atypical Conjunctival Tumor.
J Craniofac Surg
September 2024
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA.
Sarcomas are malignant tumors of connective tissue with a mesodermal origin that, in rare occasions, is presented in conjunctiva; undifferentiated pleomorphic sarcoma represents <1% of orbital tumors. It is characterized by not meeting the histologic, immunohistochemical, ultrastructural, or molecular criteria in the classification proposed by the World Health Organization. The authors present the case of an 82-year-old man, blind due to absolute glaucoma, who consulted for a conjunctival mass of a few months' evolution.
View Article and Find Full Text PDFDeciphering the Decomposition Mechanisms of Ether and Fluorinated Ether Electrolytes on Lithium Metal Surfaces: Insights from CMD and AIMD Simulations.
J Phys Chem B
August 2024
School of Materials Science and Engineering, Hunan University, Changsha 410082, China.
The performance of lithium metal batteries can be significantly enhanced by incorporating fluorinated ether-based electrolytes, yet the solid electrolyte interphase (SEI) formation mechanism on lithium metal surfaces remains elusive. This study employs classical and ab initio molecular dynamics simulations to investigate the decomposition mechanisms of lithium bis(fluoromethanesulfonyl)imide (LiFSI) in 1,2-diethoxyethane (DEE) and its fluorinated analogues, F5DEE and F2DEE, when in contact with lithium metal. Our findings indicate that F5DEE-based electrolytes favor the formation of a FSI-rich primary solvation shell around Li, while F2DEE-based electrolytes yield a solvent-rich environment.
View Article and Find Full Text PDFThe structural insight into the functional modulation of human anion exchanger 3.
Nat Commun
July 2024
Department of Orthopaedics, Shanghai Key Laboratory of Orthopaedic Implant, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Anion exchanger 3 (AE3) is pivotal in regulating intracellular pH across excitable tissues, yet its structural intricacies and functional dynamics remain underexplored compared to other anion exchangers. This study unveils the structural insights into human AE3, including the cryo-electron microscopy structures for AE3 transmembrane domains (TMD) and a chimera combining AE3 N-terminal domain (NTD) with AE2 TMD (hAE32). Our analyzes reveal a substrate binding site, an NTD-TMD interlock mechanism, and a preference for an outward-facing conformation.
View Article and Find Full Text PDFThe Fate of RPE Cells Following hESC-RPE Patch Transplantation in Haemorrhagic Wet AMD: Pigmentation, Extension of Pigmentation, Thickness of Transplant, Assessment for Proliferation and Visual Function-A 5 Year-Follow Up.
Diagnostics (Basel)
May 2024
The London Project to Cure Blindness, ORBIT, Institute of Ophthalmology, University College London (UCL), London WC1E 6BT, UK.
(1) Background: We reviewed a stem cell-derived therapeutic strategy for advanced neovascular age-related macular degeneration (nAMD) using a human embryonic stem cell-derived retinal pigment epithelium (hESC-RPE) monolayer delivered on a coated, synthetic basement membrane (BM)-the patch-and assessed the presence and distribution of hESC-RPE over 5 years following transplantation, as well as functional outcomes. (2) Methods: Two subjects with acute vision loss due to sub-macular haemorrhage in advanced nAMD received the hESC-RPE patch. Systematic immunosuppression was used peri-operatively followed by local depot immunosuppression.
View Article and Find Full Text PDFExophthalmos revealing an olfactory esthesioneuroblastoma: A case report.
Int J Surg Case Rep
June 2024
Department of Ear, Nose, Throat and Head and Neck Surgery, Farhat Hached University Hospital, Sousse, Tunisia.
Introduction And Importance: Olfactory neuroblastoma or esthesioneuroblastoma is a rare malignant tumour, that develops in the olfactory neuroepithelium and is one of the rarest tumours of the nasal cavity. Ocular manifestations are uncommon. The diagnosis is based on histology: biopsy, immunohistochemistry and ultrastructural findings.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!