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Prokineticin 1 (PROK1) is an important factor in pregnancy establishment in pigs, acting at the embryo-maternal interface and the corpus luteum (CL). Estradiol-17β (E2) is the primary pregnancy recognition signal in pigs, and its effects are augmented by luteotropic prostaglandin E2 (PGE2). On the contrary, prostaglandin F2α (PGF2α) exerts mainly a luteolytic effect.

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Steroidogenic tissues contain cytosolic lipid droplets that are important for steroidogenesis. Perilipin 2 (PLIN2), a structural coat protein located on the surface of lipid droplets in mammalian cells, plays a crucial role in regulating lipid droplet formation and contributing to various cellular processes such as lipid storage and energy homeostasis. Herein, we examine the role that PLIN2 plays in regulating progesterone synthesis in the bovine corpus luteum.

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The placenta secretes a prolactin (PRL)-like hormone PRL3B1 (placental lactogen II), a luteotropic hormone essential for maintaining pregnancy until labor in mice. A report from 1984 examined the secretion pattern of PRL3B1 in prepartum mice. In the current study, we found contradictory findings in the secretion pattern that invalidate the previous report.

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Article Synopsis
  • This study aimed to assess the effectiveness and safety of soft extracts for treating moderate ovarian hyperstimulation syndrome (OHSS) using traditional Chinese medicine principles.
  • A total of 2245 IVF/ICSI-ET patients were analyzed, with one group receiving soft extracts alongside standard treatment, and comparisons were made regarding various health indicators.
  • Results showed significant improvements in pelvic fluid absorption, maximum ovarian size, and post-procedure pain in the treatment group, with no adverse reactions reported in either group.
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Protective effect of Inonotus obliquus polysaccharide on mice infected with Neospora caninum.

Int J Biol Macromol

March 2024

Engineering Research Center of North-East Cold Region Beef Cattle Science & Technology Innovation, Ministry of Education, Yanbian University, No.977 Park Road, Yanji 133000, PR China. Electronic address:

The study aimed to explore the protective effects of Inonotus obliquus polysaccharide (IOP) on Neospora caninum (N. caninum) infection. Our data showed that the survival rate of the mice was the highest and the survival time was the longest when the IOP was 2 mg/10 g.

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