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MixDeR: A SNP mixture deconvolution workflow for forensic genetic genealogy.
Forensic Sci Int Genet
January 2025
National Bioforensic Analysis Center, National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US. Department of Homeland Security Science and Technology Directorate, 8300 Research Plaza, Fort Detrick, MD 21702, USA. Electronic address:
The generation of forensic DNA profiles consisting of single nucleotide polymorphisms (SNPs) is now being facilitated by wider adoption of next-generation sequencing (NGS) methods in casework laboratories. At the same time, and in part because of this advance, there is an intense focus on the generation of SNP profiles from evidentiary specimens for so-called forensic or investigative genetic genealogy (FGG or IGG) applications. However, FGG methods are constrained by the algorithms for genealogical database searches, which were designed for use with single-source profiles, and the fact that many forensic samples are mixtures.
View Article and Find Full Text PDFHapNetworkView: a tool for haplotype network exploration and visualization.
BMC Genomics
January 2025
Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, 100101, China.
Background: Haplotype networks are useful for investigating the genealogical relationships among haplotypes and have been extensively used in molecular evolution and population genetic studies. However, existing tools for visualizing haplotype networks lack comprehensive functionalities for data exploration and layout adjustments. Therefore, there is a need for a useful tool capable of constructing and visualizing haplotype networks, facilitating the exploration of data, particularly with datasets with large sample sizes.
View Article and Find Full Text PDFPhylogenomics and species delimitation in the Lepidophyma sylvaticum complex (Squamata: Xantusiidae) using ddRADseq and morphological data.
Mol Phylogenet Evol
January 2025
Laboratorio de Herpetología and Museo de Zoología Alfonso L. Herrera, Departamento de Biología Evolutiva, Facultad de Ciencias, Universidad Nacional Autonoma de México, Ciudad Universitaria, Coyoacán C.P. 04510, CDMX, México. Electronic address:
The Lepidophyma sylvaticum complex occurs from west-central Nuevo León to the Sierra de Chiconquiaco in central Veracruz, Mexico. Morphological studies have revealed population groups that are "moderately divergent from each other" within the complex. In addition, a molecular phylogenetic study found L.
View Article and Find Full Text PDFGenetic Composition of Polish Hucul Mare Families: mtDNA Diversity.
Genes (Basel)
December 2024
Department of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, Poland.
The Hucul horse breed formed in the region of the Eastern Carpathians, likely through the natural crossbreeding of oriental horses. After World War II, their population significantly decreased, leading to the breeding being based on only 14 female lines, whose founders often had unknown origins. To preserve the breed's unique characteristics, it is now part of a Genetic Resources Conservation Program, which prioritizes the maintenance of genetic diversity.
View Article and Find Full Text PDFIncreasing Beef Production in the Northern Region of the Republic of Kazakhstan Using the Genetic Resources of Aberdeen Angus Cattle of Different Genotypes.
Animals (Basel)
December 2024
Department of Food Security and Biotechnology, NLC «Akhmet Baitursynuly Kostanay Regional University», Kostanay 110000, Kazakhstan.
This article presents the findings of a scientific study investigating the efficacy of various assessment techniques used to evaluate the adaptability and productive qualities of Aberdeen Angus cattle on three prominent farms in the northern region of the Republic of Kazakhstan. A comprehensive analysis of the haematological and biochemical parameters of experimental groups of cattle with different genotypes (American, Canadian, and Estonian selection) was conducted. The studies revealed notable variability in haematological and biochemical indicators, contingent on the origin.
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