The expectation that important subtypes exist in dementia praecox (schizophrenia) was built into the earliest conceptualizations of this disorder by Kraepelin and Bleuler. Although the traditional subtypes are still used, more recent biological, psychological, and descriptive-clinical data suggest that quite different approaches to subtyping and subtyping categories may be more valid. No definitive answers to the subtyping problem have yet been reached, but the solution may well involve a complex consideration of biologic, psychologic, and social variables.
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http://dx.doi.org/10.1093/schbul/5.3.507 | DOI Listing |
Am J Cancer Res
April 2020
Translation Oncology Laboratory, Avera Cancer Institute Sioux Falls, SD 57105, USA.
Human Epidermal Growth Factor Receptor 2-positive breast cancer (HER2+ BC) is defined by increased amplification of the oncogene and/or overexpression of its associated HER2 transmembrane receptor protein. HER2+ BC represents approximately 15-20% of breast cancer, and it is independently associated with a higher grade, more aggressive phenotype, and worse prognosis. With the advent of trastuzumab, the prognostic landscape for HER2+ BC patients has considerably improved.
View Article and Find Full Text PDFPediatrics
March 2012
Immunization Services Division, National Center for Immunizationand Respiratory Diseases, Centers for Disease Control andPrevention, 1600 Clifton Rd NE, Atlanta, GA 30333, USA.
Schizophr Bull
November 1979
The expectation that important subtypes exist in dementia praecox (schizophrenia) was built into the earliest conceptualizations of this disorder by Kraepelin and Bleuler. Although the traditional subtypes are still used, more recent biological, psychological, and descriptive-clinical data suggest that quite different approaches to subtyping and subtyping categories may be more valid. No definitive answers to the subtyping problem have yet been reached, but the solution may well involve a complex consideration of biologic, psychologic, and social variables.
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