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Pregnant women's choices for preventing respiratory syncytial virus (RSV).
Vaccine
January 2025
Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, Adelaide, South Australia, Australia; Robinson Research Institute and Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.
Introduction: Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and pneumonia in infants and can lead to severe respiratory distress, especially in very young infants. No specific treatments exist for RSV. However, new preventative strategies have become available including RSV vaccine for pregnant women and monoclonal antibody for infants.
View Article and Find Full Text PDFConflicts of interest in the International Agency for Research on Cancer process of identifying carcinogenic hazards to humans.
Hum Exp Toxicol
January 2025
AnaPath Services GmbH/K. Weber Consulting GmbH, Oberbuchsiten, Switzerland.
Managing conflicts of interest (COIs) in scientific decision-making is important for minimizing bias and fostering public trust in science. Proper management of COIs has added significance when scientists are making decisions that impact public policy, such as assessing substances for carcinogenicity. The International Agency for Research on Cancer (IARC) organizes expert working groups to identify putative carcinogens and determine whether or not the hazard is likely to present significant potential harm to humans.
View Article and Find Full Text PDFDemonstrating performance in scaled-up production and quality control of polyhydroxyalkanoates using municipal waste activated sludge.
Water Res
January 2025
Department of Biotechnology, Delft University of Technology, Delft, The Netherlands; Wetsus, European Centre of Excellence for Sustainable Water Technology, Leeuwarden, The Netherlands; School of Chemical Engineering, University of Queensland, St. Lucia, Australia. Electronic address:
Significant progress has been made over the past decade with pilot scale polyhydroxyalkanoate (PHA) production by direct accumulation using municipal waste activated sludge (WAS). However, industrial upscaling experiences are still lacking in the research literature. In this study, a demonstration scale (4 m) PHA production process was operated using industrially relevant equipment and compared favourably to those from parallel pilot scale (200 L) production runs.
View Article and Find Full Text PDFDesigning Health Recommender Systems to Promote Health Equity: A Socioecological Perspective.
J Med Internet Res
January 2025
Department High-Tech Business and Entrepreneurship Section, Industrial Engineering and Business Information Systems, University of Twente, Enschede, Overijssel, Netherlands.
Health recommender systems (HRS) have the capability to improve human-centered care and prevention by personalizing content, such as health interventions or health information. HRS, an emerging and developing field, can play a unique role in the digital health field as they can offer relevant recommendations, not only based on what users themselves prefer and may be receptive to, but also using data about wider spheres of influence over human behavior, including peers, families, communities, and societies. We identify and discuss how HRS could play a unique role in decreasing health inequities.
View Article and Find Full Text PDFEffect of composition, temperature, and grain size on mechanical behavior and deformation mechanism of lightweight magnesium alloy.
J Mol Model
January 2025
Department of Mechanical Engineering, National Kaohsiung University of Science and Technology, Kaohsiung, 807, Taiwan.
Context: To address the severe fuel crisis and environmental pollution, the use of lightweight metal materials, such as AZ alloy, represents an optimal solution. This study investigates the mechanical behavior and deformation mechanism of AZ alloys under uniaxial compressive using molecular dynamics (MD) simulations. The influence of various compositions, grain sizes (GSs), and temperatures on the compressive stress, the ultimate compressive strength (UCS), compressive yield stress (CYS), Young's modulus (E), shear strain, phase transformation, dislocation distribution, and total deformation length is thoroughly examined.
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