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[Genetic evolution analysis of enteric cytopathogenic human orphan virus type 30 in three cases of infants and young children in Hubei Province].
Zhonghua Yu Fang Yi Xue Za Zhi
January 2025
Health Inspection and Testing Institute, Hubei Provincial Center for Disease Control and Prevention, Wuhan430079, China.
Three throat swab samples from infants and young children in Hubei Province were identified as positive for enteroviruses. All subjects were one month old, and the onset of symptoms occurred in June; these cases were sporadic and exhibited no clear epidemiological associations. The results of VP1 gene amplification analysis indicated that all three infant cases were attributed to Echovirus 30 (ECHO30).
View Article and Find Full Text PDFNeonatal acute liver failure cases with echovirus 11 infections, Japan, August to November 2024.
Euro Surveill
January 2025
President's office, National Center for Child Health and Development, Tokyo, Japan.
In 2022-23, several European countries reported paediatric acute liver failure (ALF) with enterovirus infection. In August-November 2024, three neonatal cases of ALF with echovirus 11 (E11) were reported in Tokyo, Japan. All neonates developed irreversible multiple-organ failure and died.
View Article and Find Full Text PDFOverview of the Trending Enteric Viruses and Their Pathogenesis in Intestinal Epithelial Cell Infection.
Biomedicines
December 2024
Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 33302, Taiwan.
Enteric virus infection is a major public health issue worldwide. Enteric viruses have become epidemic infectious diseases in several countries. Enteric viruses primarily infect the gastrointestinal tract and complete their life cycle in intestinal epithelial cells.
View Article and Find Full Text PDFRecent Molecular Epidemiology of Echovirus 11 Throughout North and West Africa Resulted in the First Identification of a Recombinant Strain from an Acute Flaccid Paralysis Case in West Africa.
Viruses
November 2024
Virology Department, Institut Pasteur de Dakar, 36 Avenue Pasteur, Dakar 220, Senegal.
Article Synopsis
- Echovirus 11 is causing increasing cases of neonatal sepsis in Europe and limited reports in West Africa, highlighting a significant public health issue.
- A study analyzed 23 E11 strains from West Africa using high-throughput sequencing, marking the first molecular characterization of the virus in the region and revealing a new recombinant strain.
- The research indicates that E11 has evolved into four distinct clades since the 1970s, with instances of the virus spreading from West Africa to Europe, underscoring the need for enhanced surveillance of enteroviruses in Africa.
Molecular Analysis of Coxsackievirus B2 Associated With Severe Symptoms of the Central Nervous System.
J Med Virol
November 2024
Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center, Ramat-Gan, Israel.
Coxsackievirus B2 (CVB2) is a member of the enterovirus group known to induce a spectrum of illnesses, from mild to severe. In the summer of 2022, an unusual outbreak of enteroviral central nervous system (CNS) infections occurred that was attributed to CVB2. Cerebrospinal fluid (CSF) samples collected from patients in 2015-2022 were tested for enterovirus via RT-PCR, followed by Sanger sequencing for positive cases.
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