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Femoral neck fracture in a senile patient with primary hyperparathyroidism: A case report.
Medicine (Baltimore)
November 2024
Department of Joint and Hand Orthopedics, Hunan University of Medicine General Hospital, Huaihua, China.
Rationale: As a rare cause of femoral neck fracture, usually, hyperparathyroidism is missed diagnosed by orthopedist. Patient can present with various disappearance of clinical manifestations. Primary hyperparathyroidism in senile male population is commonly an asymptomatic disorder discovered incidentally through routine lab testing.
View Article and Find Full Text PDFCausal linkage of Graves' disease with aging: Mendelian randomization analysis of telomere length and age-related phenotypes.
BMC Geriatr
October 2024
Department of Laboratory Medicine, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
Background: Aging is an irreversible progressive decline in physical function. Graves' disease (GD) is a common cause of hyperthyroidism and is characterized by elevated levels of the thyroid hormone (TH). High TH levels are associated with aging and a shortened lifespan.
View Article and Find Full Text PDFCausal relationship between hyperthyroidism and cataracts: a two-sample bi-directional mendelian randomization study.
Sci Rep
October 2024
Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Clinical studies and meta-analyses have suggested a link between thyroid dysfunction and lens opacification. The objective of this study is to investigate the causal relationship between hyperthyroidism and the development of cataracts using the Mendelian randomization approach, with the aim of filling the gap in knowledge about the systemic effects of hyperthyroidism on ocular health. Leveraging genetic variants as instrumental variables, the analysis used extensive datasets from the UK Biobank and the FinnGen Database and employed three common approaches for causal inference (the Inverse Variance Weighted method, a regression based method the Weighted Median estimator, and MR-Egger regression) and accompanying sensitivity analyses to ensure robustness.
View Article and Find Full Text PDFAge-Appropriate Cancer Screenings Through a Dermatology Len.
WMJ
September 2023
Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin,
Background: Primary care physicians are often the first to identify signs and symptoms concerning for cancer. An important aspect of cancer screening is thorough skin examinations and subsequent referral to a dermatologist for atypical cutaneous presentations, which may be associated with an underlying visceral malignancy. Diagnostic considerations for pruritus without dermatitis ("itch without rash") in adults include senile pruritus, medication reaction, and paraneoplastic syndrome.
View Article and Find Full Text PDFRetraction notice to "KDM5B-mediated microRNA-448 up-regulation restrains papillary thyroid cancer cell progression and slows down tumor growth via TGIF1 repression" [Life Sci. 250 (2020) 117519].
Life Sci
August 2023
Senile Endocrinology, Xiangya Hospital Central South University, Changsha 410008, Hunan, China.
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