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Multiscale interstitial fluid computation modeling of cortical bone to characterize the hydromechanical stimulation of lacunar-canalicular network.
Bone
December 2024
College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi, China.
Bone tissue is a biological composite material with a complex hierarchical structure that could continuously adjust its internal structure to adapt to the alterations in the external load environment. The fluid flow within bone is the main route of osteocyte metabolism, and the pore pressure as well as the fluid shear stress generated by it are important mechanical stimuli perceived by osteocytes. Owing to the irregular multiscale structure of bone tissue, the fluid stimulation that lacunar-canalicular network (LCN) in different regions of the tissue underwent remained unclear.
View Article and Find Full Text PDFUtility of narrow band imaging in a patient with a spinal cord cavernous malformation.
Eur Spine J
December 2024
Department of Neurosurgery, Medical Research Institute KITANO HOSPITAL, PIIF Tazuke-Kofukai, Osaka, Japan.
Background: Complete removal of the lesion from the spinal cord cavernous malformation is crucial in patients with spinal cord cavernous malformation. Herein, we report that narrow-band imaging (NBI) is useful to confirm the complete removal of spinal cord cavernous malformations.
Clinical Presentation: A 45-year-old woman was followed up for the past seven years due to multiple intracranial cavernous malformations.
Duraplasty promotes functional recovery by alleviating intraspinal pressure and edema following severe spinal cord compression injury in rabbits: experimental studies.
Spine J
December 2024
Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing 400016, China; Orthopedic Laboratory of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing 400016, China. Electronic address:
Background: After acute traumatic spinal cord injury (tSCI), various surgical strategies have been developed to alleviate elevated intraspinal pressure (ISP) and secondary injury.
Purpose: Our study aimed to investigate the impacts of duraplasty and laminectomy on edema progression, perfusion and functional outcomes after severe balloon compression SCI.
Study Design: In vivo animal study.
GsMTx4 Combined with Exercise Exerts Neuroprotective Effects by Regulating Neuronal Autophagy in Rats with Spinal Cord Injury.
Neurochem Res
December 2024
School of Sport Medicine and Rehabilitation, Beijing Sport University, Beijing, 100084, China.
A sharp increase in intramedullary pressure after spinal cord injury (SCI) can aggravate secondary injury and lead to severe neurological deficits. Unfortunately, effective treatment options are currently lacking. The mechanosensitive ion channel Piezo1 plays an important role in the pathological process of SCI by transducing mechanical stress.
View Article and Find Full Text PDFClosed Intramedullary Pinning of Displaced Radial Neck Fracture (Metaizeau Technique).
JBJS Essent Surg Tech
November 2024
Pediatric Hand, Nerve and Microsurgery, Barcelona Children's Hospital, HM Hospitales, Barcelona, Spain.
Background: Radial neck fractures account for 1% of all pediatric fractures and 5% to 10% of pediatric elbow fractures. The mechanism of injury is typically a fall with the elbow in hyperextension and the forearm in supination. A valgus force compresses the radial head against the capitellum, causing a radial neck fracture.
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