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Using the Key Characteristics Framework to Unlock the Mysteries of Aryl Hydrocarbon Receptor-Mediated Effects on the Immune System.
Annu Rev Immunol
January 2025
3Department of Environmental Medicine and Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA; email:
Initially discovered for its role mediating the deleterious effects of environmental contaminants, the aryl hydrocarbon receptor (AHR) is now known to be a crucial regulator of the immune system. The expanding list of AHR ligands includes synthetic and naturally derived molecules spanning pollutants, phytochemicals, pharmaceuticals, and substances derived from amino acids and microorganisms. The consequences of engaging AHR vary, depending on factors such as the AHR ligand, cell type, immune challenge, developmental state, dose, and timing of exposure relative to the immune stimulus.
View Article and Find Full Text PDFFeature selectivity of corticocortical feedback along the primate dorsal visual pathway.
J Neurophysiol
January 2025
Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada.
Anatomical studies have revealed a prominent role for feedback projections in the primate visual cortex. Theoretical models suggest that these projections support important brain functions, like attention, prediction, and learning. However, these models make different predictions about the relationship between feedback connectivity and neuronal stimulus selectivity.
View Article and Find Full Text PDFWhen a neutral stimulus is paired with a stimulus denoting an attribute, the neutral stimulus inherits that attribute (i.e., Attribute Conditioning; AC).
View Article and Find Full Text PDFMicrosaccade selectivity as discriminative feature for object decoding.
iScience
January 2025
School of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran 14399-57131, Iran.
Microsaccades, a form of fixational eye movements, help maintain visual stability during stationary observations. This study examines the modulation of microsaccadic rates by various stimulus categories in monkeys and humans during a passive viewing task. Stimulus sets were grouped into four primary categories: human, animal, natural, and man-made.
View Article and Find Full Text PDFUnderstanding the adoption intention of financial data retrieval services: An empirical analysis of my data.
Heliyon
January 2025
Division of Information & Communication Engineering, Kongju National University, Cheonan-daero, Cheonan, 31080, Republic of Korea.
This study empirically analyzed the variables affecting the adoption intention of a financial data retrieval service (i.e. My Data) through the convergence of the stimulus-organism-response (S-O-R) model, the value-based adoption model (VAM), and the unified theory of acceptance and use of technology (UTAUT1).
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