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Pancytopenia related to acquired sea-blue histiocytosis during chronic parenteral nutrition.
Am J Hematol
May 2024
Service d'Hématologie Biologique, Hôpital Beaujon, AP-HP Nord Université de Paris, Clichy, France.
Bone marrow smear showing histiocytes (black arrow) containing sea blue granules stained with May-Grünwald Giemsa.
View Article and Find Full Text PDFSea-blue histiocytosis.
Ann Pathol
March 2024
Pediatric Surgery Department, Complejo Asistencial Universitario de León, León, Spain.; Hospital Universitario de Navarra, Pamplona, Navarra, Spain. Electronic address:
A 78-year-old woman with hypertrophic cardiomyopathy underwent a septal myomectomy and valve replacement. In the immediate postoperative period she developed shock of mixed etiology and died. At autopsy, hepatomegaly and splenomegaly were identified, with PAS and Giemsa positive intracellular ceroid granular deposits.
View Article and Find Full Text PDFSea-blue histiocytes in the bone marrow of a patient with Niemann-Pick disease type C2.
Ann Biol Clin (Paris)
August 2020
Laboratoire d'hématologie, Groupe Hospitalier de la région Mulhouse Sud Alsace, Mulhouse, France.
A progressive neurological condition with acquired sea-blue histiocytosis further the diagnosis of Niemann-Pick type C1 in a 10-year-old boy.
Indian J Pathol Microbiol
January 2021
Department of Pathology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Sea-blue histiocytes in bone marrow can be associated with a number of conditions and have indeed often been reported in Niemann-Pick diseases, mostly in Niemann-Pick type B, but also Niemann-Pick type C. Rarely, it was reported to be related to a progressive neurological condition. In this work, early bone marrow aspirations in a boy following the discovery of hepatosplenomegaly at 1 month of age and later isolated splenomegaly did not reveal abnormal cells (which is not uncommon).
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