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Lasers Med Sci
January 2025
Post Graduate Program in Medicine-Biophotonics, Nove de Julho University / UNINOVE, São Paulo, Brazil.
This brief report aimed to investigate the optical absorbance spectra of normal, dysplastic, and malignant epithelial cell lines under normal and nutritional stress conditions. HaCAT (keratinocyte), DOK (oral dysplastic), and oral squamous cell carcinoma (OSCC) cell lines (CA1, Luc4, SCC9) were evaluated regarding their optical absorbance after culture with 0-10% fetal bovine serum. Absorbance measurements indicated that HaCAT under serum starvation exhibited higher absorbance at blue (430 nm) and near-infrared (906 nm) wavelengths.
View Article and Find Full Text PDFMater Today Bio
February 2025
State Key Laboratory of Digital Medical Engineering, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Sciences & Medical Engineering, Southeast University, Nanjing, 210009, China.
Hepatocellular carcinoma (HCC) is a major public health threat due to its high incidence and mortality rates. Transcatheter arterial chemoembolization (TACE), the primary treatment for intermediate-to-advanced hepatocellular carcinoma (HCC), commonly utilizes embolic agents loaded with anthracycline-based cytotoxic drugs. Post-TACE, the hypoxic microenvironment in the tumor induced by embolization stimulates the formation of new blood vessels, potentially leading to revascularization and diminishing TACE's efficacy.
View Article and Find Full Text PDFPlant Cell Environ
January 2025
Department of Plant Nutriton, Root Biology Center, State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Natural Resources and Environment, South China Agricultural University, Guangzhou, China.
Plant internal phosphorus (P) recycling is a complex process, which is vital for improving plant P use efficiency. However, the mechanisms underlying phosphate (Pi) release from internal organic-P form remains to be deciphered in crops. Here, we functionally characterised a Pi-starvation responsive purple acid phosphatase (PAP), GmPAP23 in soybean (Glycine max).
View Article and Find Full Text PDFOver lifetime, organisms can be repeatedly exposed to stress, shaping their phenotype. At certain, so-called sensitive phases, individuals might be more receptive to such stress, for example, nutritional stress. However, little is known about how plastic responses differ between individuals experiencing nutritional stress early versus later in life or repeatedly, particularly in species with distinct ontogenetic niches.
View Article and Find Full Text PDFG3 (Bethesda)
January 2025
Department of Biology, Duke University, Durham, NC 27708, USA.
Insulin/IGF signaling (IIS) regulates developmental and metabolic plasticity. Conditional regulation of insulin-like peptide expression and secretion promotes different phenotypes in different environments. However, IIS can also be regulated by other, less-understood mechanisms.
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