Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0301-4622(73)80001-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impact of menopause and age on breast density and background parenchymal enhancement in dynamic contrast-enhanced magnetic resonance imaging.
J Med Imaging (Bellingham)
November 2025
University of Toronto, Department of Medical Biophysics, Toronto, Ontario, Canada.
Purpose: Breast density (BD) and background parenchymal enhancement (BPE) are important imaging biomarkers for breast cancer (BC) risk. We aim to evaluate longitudinal changes in quantitative BD and BPE in high-risk women undergoing dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), focusing on the effects of age and transition into menopause.
Approach: A retrospective cohort study analyzed 834 high-risk women undergoing breast DCE-MRI for screening between 2005 and 2020.
GDF15 Circulating Levels Are Associated with Metabolic-Associated Liver Injury and Atherosclerotic Cardiovascular Disease.
Int J Mol Sci
February 2025
Research Unit on Lipids and Atherosclerosis, University Rovira i Virgili, 43201 Reus, Spain.
There is growing evidence linking growth differentiation factor 15 (GDF15) to both metabolic dysfunction-associated steatotic liver disease (MASLD) and cardiovascular (CV) risk. Nevertheless, the potential relationship between circulating levels of GDF15 and key features of MASLD being predisposed to atherosclerotic CV disease is not fully unveiled. The aim of this study was to deepen into the role of circulating GDF15 levels on metabolic-associated liver injury and atherosclerotic CV disease.
View Article and Find Full Text PDFSpectroscopic Characterization Using H and C Nuclear Magnetic Resonance and Computational Analysis of the Complex of Donepezil with 2,6-Methyl-β-Cyclodextrin and Hydroxy Propyl Methyl Cellulose.
Molecules
March 2025
Department of Chemistry, National and Kapodistrian University of Athens, Zografou, 15771 Athens, Greece.
Donepezil (DH), a selective acetylcholinesterase inhibitor, is widely used to manage symptoms of mild to moderate Alzheimer's disease by enhancing cholinergic neurotransmission and preventing acetylcholine breakdown. Despite the effectiveness of oral formulations, extensive hepatic metabolism and low systemic bioavailability have driven the search for alternative delivery systems. This study focuses on nasal delivery as a non-parenteral substitute, utilizing hydroxypropyl methylcellulose (HPMC) for its mucoadhesive properties and methyl-β-cyclodextrin (Me-β-CD) for its ability to enhance permeability and form inclusion complexes with drugs.
View Article and Find Full Text PDFAxial Ligand Effects on the Mechanism of Ru-CO Bond Photodissociation and Photophysical Properties of Ru(II)-Salen PhotoCORMs/Theranostics: A Density Functional Theory Study.
Molecules
March 2025
Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Density functional theory (DFT) calculations were employed to study a series of complexes of general formula [Ru(salen)(X)(CO)] (X = Cl, F, SCN, DMSO, Phosphabenzene, Phosphole, TPH, CN, N, NO, CNH, NHC, P(OH), PF, PH). The effect of ligands X on the Ru-CO bond was quantified by the -philicity, ΔC NMR parameter. The potential of ΔC to be used as a probe of the CO photodissociation by Ru(II) transition metal complexes is established upon comparing it with other -effect parameters.
View Article and Find Full Text PDFSchiff Base Compounds Derived from 5-Methyl Salicylaldehyde as Turn-On Fluorescent Probes for Al Detection: Experimental and DFT Calculations.
Molecules
February 2025
School of Chemistry, South China Normal University, Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine, GDMPA Key Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals, Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, Guangzhou 510006, China.
Using 5-methyl salicylaldehyde () as a reactant to react with different amines, 2-aminobenzimidazole (), 2-aminobenzothiazole (), and 2-aminopyridine (), respectively, three types of Schiff base fluorescent probes - were designed and synthesized for selective detection of Al in aqueous media. The structure of the compounds was acquired by H NMR, C NMR, and X-ray single-crystal diffraction. Furthermore, their photochromic and fluorescent behaviors have been investigated systematically by fluorescence spectra.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!