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Schistosomiasis is a neglected tropical disease of public health significance. In view of its elimination as a public health problem by 2030, adopting a One Health approach is necessary, considering its multidimensional nature. Animal reservoirs, in particular, pose a significant threat to schistosomiasis control in Africa and beyond.

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Background: Schistosomiasis is an important snail-borne parasitic disease whose transmission is exacerbated by water resource management activities. In Rwanda, meeting the growing population's demand for food has led to wetlands reclamation for cultivation and increased agrochemical enrichment for crop production. However, the ecological consequences of agrochemical enrichment on schistosomiasis transmission remain unexplored.

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Molecular insights into the physiological impact of low-frequency noise on sea slug Onchidium reevesii: Activation of p53 signaling and oxidative stress response.

J Environ Manage

January 2025

International Research Center for Marine Biosciences, Shanghai Ocean University, Ministry of Science and Technology, College of Fisheries and Life Science, Shanghai, 201306, China. Electronic address:

To investigate the regulatory role of tumor protein p53 of sea slug (Onchidium reevesii) under oxidative stress conditions, we examined the response mechanisms of O. reevesii to low-frequency noise pollution (1000 Hz) using molecular and cellular biology techniques. We successfully cloned the O.

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Molluscicidal Activity of Extracts and Fractions From , , and Against and Snails.

J Parasitol Res

November 2024

Department of Microbial, Cellular and Molecular Biology, College of Natural and Computational Sciences, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia.

: Schistosomiasis continues to be a major public health concern in Ethiopia. Eliminating the intermediate host snails is an effective and cost-efficient strategy for preventing and controlling schistosomiasis transmission. However, chemical molluscicides have limitations due to their toxicity to nontarget aquatic organisms, environmental concerns, and the development of resistance.

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Article Synopsis
  • The World Health Organization (WHO) aims to eliminate schistosomiasis globally by 2030, with chemical control of the Bulinus snail species being a key strategy for reducing transmission on Pemba Island, Tanzania.
  • Conducted malacological surveys among water bodies over three years found that the presence of Bulinus was influenced by environmental factors, with a notable decrease in their presence following niclosamide treatment.
  • The study observed variable infestation levels across different hotspots and identified a pattern where some water bodies saw recurring Bulinus even after initial control measures were applied.
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