Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Dipnictogen Radical Chemistry: A Dithorium-Supported Distibene Radical Trianion.
J Am Chem Soc
January 2025
Department of Chemistry and Centre for Radiochemistry Research, The University of Manchester, Oxford Road, Manchester M13 9PL, U.K.
Although two examples of σ-bonded -bent [RSbSbR] (R = bulky organo- or Ga-groups) that formally contain the Sb radical trianion moiety are known in p-block chemistry, d- or f-element Sb radical trianion complexes, with or without R-substituents, have remained elusive. Here, we report that reduction of a 77:23 mix of [{Th(Tren)}(μ-η:η-Sb)] (, Tren = {N(CHCHNSiPr)}):[{Th(Tren)}(μ-SbH)] () with 1.5 equiv of KC in the presence of 1.
View Article and Find Full Text PDFDiscovery of selective ROCK2 inhibitors with free radical scavenging ability for the treatment of gouty arthritis.
Mol Divers
January 2025
Key Laboratory of Structure-Based Drugs Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, PR China.
ROCK inhibitors can inhibit IL-1β and NLRP3, and their therapeutic potential for osteoarthritis and rheumatoid arthritis has been confirmed, but their impact on gouty arthritis has not been reported yet. By hybridization the structure of Edaravone, a series of ROCK inhibitors with pyrazolone scaffold were designed and synthesized. RM-04 has acceptable selective ROCK2 inhibitory activity with an IC of 4.
View Article and Find Full Text PDFValue of Noncontrast-Enhanced Vessel Wall MRI in Longitudinal Venous System Invasion Before Robot-Assisted Radical Nephrectomy.
J Endourol
January 2025
Department of Radiology, Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
To explore the value of vessel wall MRI (VW-MRI) in the preoperative assessment of T3 renal-cell carcinoma (RCC) with varying degrees of longitudinal venous system invasion. Patients with RCC with pathological T3 stage between January 2016 and December 2023 were included in this retrospective study. All the patients underwent contrast-enhanced CT (CECT), conventional MRI (con-MRI) or VW-MRI.
View Article and Find Full Text PDFTheoretical Study on the Kinetics of Secondary Oxygen Addition Reactions for N-Butyl Radicals.
J Phys Chem A
January 2025
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Frontiers Science Center of Molecule Intelligent Syntheses, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.
Chemical kinetics for second oxygen addition reactions (·QOOH + O) of long-chain alkanes are of great importance in low-temperature combustion technologies. However, kinetic data for key reactions of ·QOOH + O systems are often difficult to obtain experimentally and are primarily estimated or calculated by using theoretical methods. In this work, barrier heights (BHs), reaction energies (Δs), and relative energies (REs) of stationary points for key reactions of two representative ·QOOH + O systems in the low-temperature oxidation of -butyl as well as pressure-dependent rate constants for the involved reactions are calculated with the high-level quantum chemical method CCSD(T)-F12b/CBS.
View Article and Find Full Text PDFUpcycling of Organic and Inorganic Waste into MIL-88B(Fe) at Room Temperature for Tetracycline Degradation.
Inorg Chem
January 2025
College of Chemistry, Chemical Engineering and Environment, Minnan Normal University, Zhangzhou 363000, China.
Upcycling organic and inorganic waste into value-added metal-organic frameworks (MOFs) presents a sustainable strategy for mitigating waste pollution and promoting economic viability. However, rapid synthesis of MOF materials derived from actual industrial waste under mild conditions remains challenging. Herein, Fe-MOF MIL-88B(Fe) was successfully fabricated within 1 h at room temperature using galvanizing pickling waste liquid and terephthalic acid derived from waste poly(ethylene terephthalate).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!