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A high lipid diet leads to greater pathology and lower tolerance during infection.
J Exp Biol
January 2025
Dept of Biological Sciences, University of Arkansas, Fayetteville AR 72701, USA.
Altered food landscapes contribute importantly to wildlife disease dynamics and may play an important role in host heterogeneity in disease outcomes through changes in host diet composition. We explored the effects of dietary macronutrient composition on disease pathology and feeding behavior of canaries (Serinus canaria domestica) infected with Mycoplasma gallisepticum (MG). In the first experiment, we provided canaries with isocaloric diets comprised of identical ingredients that varied in macronutrient content (high-protein or high-lipid) then MG- or sham-inoculated birds.
View Article and Find Full Text PDFTransabdominal laparoscopic excision of a giant retroperitoneal lymphangioma.
S Afr J Surg
December 2024
Department of Gastrointestinal Surgery, Central Hospital Affiliated to Shandong First Medical University, China.
Retroperitoneal lymphangioma is exceptionally rare. We present a case of a 41-year-old asymptomatic patient with a large abdominal cystic mass detected on contrast-enhanced computed tomography (CT) scan, initially suspected to be pseudomyxoma peritonei. Laparoscopic exploration revealed a 30 x 30 cm multilocular cystic tumour originating from the retroperitoneum.
View Article and Find Full Text PDFThe dynamic crosstalk between cytoskeletal filaments regulates the cytoplasmic mechanics across the dorsoventral axis.
J Cell Sci
January 2025
School of Biological Sciences, Indian Association for the Cultivation of Science, Kolkata-700032, India.
The cytoplasm exhibits viscoelastic properties, displaying both solid and liquid-like behavior, and can actively regulate its mechanical attributes. The cytoskeleton is a major regulator among the numerous factors influencing cytoplasmic mechanics. We explore the interdependence of various cytoskeletal filaments and the impact of their density on cytoplasmic viscoelasticity.
View Article and Find Full Text PDFRepresentative modeling of biocompatible MXene nanocomposites for next-generation biomedical technologies and healthcare.
J Mater Chem B
January 2025
Department of Advanced Materials Science & Engineering, Hanseo University, Seosan, Chungnam 31962, Republic of Korea.
MXenes are a class of 2D transition metal carbides and nitrides (MXT) that have attracted significant interest owing to their remarkable potential in various fields. The unique combination of their excellent electromagnetic, optical, mechanical, and physical properties have extended their applications to the biological realm as well. In particular, their ultra-thin layered structure holds specific promise for diverse biomedical applications.
View Article and Find Full Text PDFMelatonin Overexpression in the Management of Alzheimer's Disease: Therapeutic Exploration.
Curr Top Med Chem
January 2025
Graphic Era (Deemed to be University), Clement Town Dehradun, India.
Alzheimer's Disease (AD), a progressive neurodegenerative disorder, is characterized by the accumulation of neurofibrillary tangles and β-amyloid plaques, leading to a decline in cognitive function. AD is characterized by tau protein hyperphosphorylation and extracellular β-amyloid accumulation. Even after much research, there are still no proven cures for AD.
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