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Ectopic Papillary Thyroid Cancer: About a Case.
Cureus
October 2024
Surgery, Specialties Hospital "Dr. Antonio Fraga Mouret" La Raza National Medical Center of the Mexican Institute of Social Security (IMSS), Mexico City, MEX.
Cervical lymph nodes can indicate various inflammatory or cancerous conditions. Ectopic thyroid carcinoma, particularly papillary carcinoma, can be found in resected lymph nodes even without clinical thyroid abnormalities, known as hidden (incidental) metastasis. We present the case of a 42-year-old woman with a 5 cm thyroid nodule and associated symptoms.
View Article and Find Full Text PDFAnalysis of T follicular and T peripheral helper lymphocytes in autoimmune thyroid disease.
Endocrine
November 2024
Service of Endocrinology, Hospital Universitario de La Princesa, Instituto de Investigación Princesa, Universidad Autónoma de Madrid, Madrid, España.
Purpose: Peripheral helper T (Tph) cells have an important role in the induction of humoral immune responses and autoantibody production. Accordingly, it is feasible that this lymphocyte subset has a relevant role in the pathogenesis of autoimmune thyroid diseases (AITD). In this study we aim to analyze the levels and function of Tph cells in blood samples from patients with AITD.
View Article and Find Full Text PDFNovel pathogenic variant of in an adolescent with multinodular goiter, ovarian Sertoli-Leydig cell tumor and pineal parenchymal tumor of intermediate differentiation.
J Pediatr Endocrinol Metab
August 2023
Master of Science, Endocrinology Department, Hospital de Especialidades, UMAE CMN Siglo XXI, IMSS, Avenida Cuauhtémoc N. 330 Colonia Doctores. C.P. 06720, Mexico City, Mexico.
Article Synopsis
- A 13-year-old girl exhibited symptoms of a non-toxic multinodular goiter and developed an ovarian Sertoli-Leydig cell tumor, alongside a pineal parenchymal tumor.
- Next-generation sequencing identified a new pathogenic variant in the DICER1 gene, specifically a germline mutation (exon 16, c2488del [pGlu830Serfs*2]).
- This case highlights that mutations in the DICER1 gene can lead to a genetic predisposition for various types of tumors, ranging from benign to malignant, throughout a person's life.
Long-Term Lithium Therapy and Thyroid Disorders in Bipolar Disorder: A Historical Cohort Study.
Brain Sci
January 2023
Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN 55905, USA.
Lithium has been a cornerstone treatment for bipolar disorder (BD). Despite descriptions in the literature regarding associations between long-term lithium therapy (LTLT) and development of a thyroid disorder (overt/subclinical hypo/hyperthyroidism, thyroid nodule, and goiter) in BD, factors such as time to onset of thyroid abnormalities and impact on clinical outcomes in the course of illness have not been fully characterized. In this study we aimed to compare clinical characteristics of adult BD patients with and without thyroid disorders who were on LTLT.
View Article and Find Full Text PDF[Multimodal anesthesia in a patient with Graves' disease and thyrotoxicosis: A case report].
Rev Med Inst Mex Seguro Soc
August 2022
Instituto Mexicano del Seguro Social, Centro Médico Nacional La Raza, Hospital General "Dr. Gaudencio González Garza", Servicio de Anestesiología Pediátrica. Ciudad de México, México.
Article Synopsis
- Hyperthyroidism, while rare in children, peaks in adolescence, particularly in females, and can lead to severe complications like thyroid storm in poorly managed cases.
- A clinical case details a 17-year-old with uncontrolled Graves' disease undergoing radical thyroidectomy, where a high score on the Burch and Wartofsky Scale indicated significant risk.
- The use of multimodal anesthesia during surgery effectively prevented a thyroid storm and minimized postoperative pain and complications.
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