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Re-evaluating large for gestational age: differential effects on perinatal outcomes in term and premature births.
Front Med (Lausanne)
January 2025
Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Objective: Pregnancies with large-for-gestational-age (LGA) fetuses are associated with increased risks of various adverse perinatal outcomes. While existing research primarily focuses on term neonates, less is known about preterm neonates. This study aims to explore the risks of adverse maternal and neonatal perinatal outcomes associated with LGA in term neonates and neonates with different degrees of prematurity, compared to appropriate-for-gestational-age (AGA) neonates.
View Article and Find Full Text PDFTranscript Changes of Placental Tissue in Gestational Diabetes Mellitus Based on Transcriptome Sequencing.
Diabetes Metab Syndr Obes
January 2025
Department of Obstetrics, The Affiliated Taian City Central Hospital of Qingdao University, Taian, People's Republic of China.
Purpose: This study aims to identify key genes that may be involved in the pathogenesis of gestational diabetes mellitus and to preliminarily elucidate the underlying mechanisms.
Methods: High-throughput transcriptome sequencing was employed to identify Differentially expressed genes (DEGs) in placental tissue samples of GDM and normal pregnant women. Functional and pathway analyses of these DEGs were conducted using bioinformatics databases.
Association Between Maternal Periodontitis and Adverse Pregnancy Outcomes: A Cross-Sectional Study at a Maternity Hospital in Kathmandu, Nepal.
Cureus
December 2024
Department of Public Health, National Open College, Lalitpur, NPL.
Background: Adverse pregnancy outcomes, including preterm birth and low birth weight, are major global health challenges, leading to millions of newborn deaths each year. Since 1996, periodontitis and related gum diseases have been proposed as potential contributing factors, but research findings remain mixed. Further research is needed to clarify this link.
View Article and Find Full Text PDFVulvar Carcinoma in Pregnancy: A Case Report on Diagnosis, Management, and Surgical Outcomes.
Cureus
December 2024
Obstetrics and Gynaecology, Fernandez hospital, Hyderabad, IND.
Vulvar cancer is an uncommon malignancy in reproductive-aged women, and its occurrence during pregnancy is rare. This report presents a case of vulvar squamous cell carcinoma (VSCC) diagnosed perioperatively in a 35-year-old pregnant woman. The patient was incidentally found to have lichen sclerosis and a suspicious vulvar lesion during an emergency cesarean section.
View Article and Find Full Text PDFA Case of Latent Syphilis in Early Pregnancy: An Incidental Finding at Seven Weeks Gestation.
Cureus
December 2024
Internal Medicine, Thumbay University Hospital, Ajman, ARE.
, the bacteria that causes syphilis, is typically acquired through sexual contact but can also be transmitted transplacentally (through the placenta), causing congenital infection. Syphilis in pregnancy is a major contributing factor to perinatal morbidity and mortality. Untreated neonates may develop complications affecting the central nervous system, bones, joints, teeth, eyes, and skin.
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