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Utility of colposcopy for the screening and management of cervical cancer in Africa: a cross-sectional analysis of providers' training and practices.
BMC Health Serv Res
December 2024
Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, 1400 Pressler Dr., FCT4.6002, Houston, TX, 77030, USA.
Introduction: Cervical cancer is a public health issue in Africa with devastating socioeconomic consequences due to the lack of organized screening programs. The success of screening programs depends on the appropriate investigation and management of women who test positive for screening. Colposcopic assessment following positive screening results is a noteworthy issue in Africa.
View Article and Find Full Text PDF[Translocation-associated uterine mesenchymal tumors: The new without forgetting the old. An integrated diagnostic approach].
Ann Pathol
January 2025
Département de biopathologie, institut Bergonié, Bordeaux, France; Unité Inserm 1312, Bordeaux, France.
This review focuses on uterine mesenchymal tumors that are defined on a molecular level by a single and unique genetic alteration, that is somehow necessary and sufficient to allow tumor growth and progression. Although diverse from a clinical, morphological and immunohistochemical point of view, the different entities we are going to talk about share both a simple genomic profile with a low number of chromosomal alterations observed by CGH Array (few deletions, gains or amplifications..
View Article and Find Full Text PDFEstimation of self-funded human papillomavirus vaccine recipients from Japan's previously assumed "unvaccinated generation".
Cancer Sci
September 2024
Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Osaka, Suita-City, Osaka, Japan.
Precise vaccination data is essential to accurately estimate the effectiveness of the human papillomavirus (HPV) vaccine against HPV-related cancers. In Japan, the number of subsidized HPV vaccinations can be tracked through registries, but the number of self-funded vaccinations has not been tracked. The number of individuals who chose to receive the vaccine at their own expense, despite being ineligible for public subsidies due to their age, is unknown and has been nominally considered to be zero.
View Article and Find Full Text PDFHPV vaccination in Africa in the COVID-19 era: a cross-sectional survey of healthcare providers' knowledge, training, and recommendation practices.
Front Public Health
February 2024
Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Introduction: Although the burden of cervical cancer in Africa is highest, HPV vaccination coverage remains alarmingly low in this region. Providers' knowledge and recommendation are key drivers of HPV vaccination uptake. Yet, evidence about providers' knowledge and recommendation practices about the HPV vaccine against a backdrop of emerging vaccine hesitancy fueled by the COVID-19 pandemic is lacking in Africa.
View Article and Find Full Text PDFMargin status after loop electrosurgical excision procedure (LEEP) and laser excision in patients with high-grade cervical neoplasia.
J Gynecol Obstet Hum Reprod
January 2024
Gynecologic and Breast Oncologic Surgery Department, Georges Pompidou European Hospital, APHP. Centre, Université de Paris, 20, rue Leblanc 75908, Paris Cedex 15, Paris, France; INSERM UMR-S 1147, Université Paris Cité, Centre de Recherche des Cordeliers, Paris, France.
Article Synopsis
- Early management of high-grade cervical intraepithelial neoplasia is vital for cervical cancer prevention, with both loop electro excision (LEEP) and laser excision methods being effective techniques recommended for lesion removal.
- The study aimed to compare these two methods, focusing on the quality of surgical margins, and was conducted on 231 patients over an 8-year period.
- Results showed no significant difference in negative margin rates between the two techniques, but LEEP was associated with a shorter cone depth in excisions performed.
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