Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Gi-protein-coupled β -adrenergic receptor: re-understanding the selectivity of β -adrenergic receptor to G protein.
Acta Biochim Biophys Sin (Shanghai)
August 2022
Department of Physiology & Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.
β -adrenergic receptor (β -AR), a member in the family of G-protein-coupled receptors, is a transmembrane receptor of great significance in the heart. Physiologically, catecholamines activate β -AR to initiate a positive chronotropic, inotropic, and dromotropic change. It is believed that β -AR couples to Gs protein and transmits the signal through second messenger cAMP.
View Article and Find Full Text PDFTransient ascending ST-segment depression and widening of the S wave in 3-channel Holter monitoring-A sign of dromotropic disturbance in the right ventricular outflow tract in the Brugada syndrome: A report of five cases.
Ann Noninvasive Electrocardiol
March 2022
Laboratório de Delineamento de Estudos e Escrita Científica, Centro Universitário FMABC, Centro Universitário FMABC, Santo André, Brazil.
Article Synopsis
- Brugada syndrome (BrS) is difficult to diagnose due to its dynamic symptoms, primarily involving conduction disorders in the right ventricular outflow tract caused by low Connexin-43 expression, which affects the heart's electrical signals as seen on an electrocardiogram (ECG).
- During Holter monitoring of five cases with intermittent type 1 BrS, significant changes like ascending ST segment depression and S wave widening were observed, primarily in lead C2, with occasional involvement of C1 and C3.
- The ECG patterns noted in this exploratory analysis should alert healthcare providers to the possibility of BrS, indicating underlying conduction disturbances in the heart’s right side.
Analysis of electropharmacological and proarrhythmic effects of donepezil using the halothane-anesthetized intact dogs and the conscious chronic atrioventricular block ones.
Naunyn Schmiedebergs Arch Pharmacol
April 2021
Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan.
Donepezil, an inhibitor for acetylcholinesterase used for patients with Alzheimer's disease, has been shown to inhibit I, occasionally inducing torsade de pointes. In order to analyze the causal relationship between donepezil treatment and onset of lethal arrhythmias, we initially assessed electropharmacological effects of donepezil hydrochloride of 0.01, 0.
View Article and Find Full Text PDFEffect of gallic acid on electrophysiological properties and ventricular arrhythmia following chemical-induced arrhythmia in rat.
Iran J Basic Med Sci
February 2020
Department of Physiology, Persian Gulf Physiology Research Center, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Objectives: Ventricular arrhythmias including ventricular tachycardia (VT) and ventricular fibrillation (VF) are the most important causes of mortality rate. Gallic acid (GA) has beneficial effects on cardiovascular diseases. The aim of this study was to evaluate the effects of GA on electrophysiological parameters such as QRS complex, heart rate (HR), PR interval parameters, and ventricular arrhythmia following chemical induction in rat.
View Article and Find Full Text PDFTransient left anterior and septal fascicular blocks after self-expandable percutaneous transcatheter aortic valve implantation.
Ann Noninvasive Electrocardiol
July 2019
Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Transcatheter aortic valve implantation (TAVI) is indicated in severe symptomatic aortic stenosis, when there is intermediate-high surgical risk, or a condition considered inoperable, as in the case of "porcelain aorta" that could turn clamping or cannulation of the ascending aorta hazardous in open-heart surgery. Among the complications of this less invasive procedure, intraventricular conduction disorders subsequent to the procedure stand out. TAVI causes worsening of intraventricular dromotropic disorders in more than 75% of the cases, with the presence of preexisting right bundle branch block and first-degree atrioventricular block, deep prosthesis implant, male gender, size of the aortic annulus smaller than the prosthesis, and porcelain aorta being predictive of requirement for permanent pacemaker implant.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!