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Transcriptional and biochemical changes in mouse liver following exposure to a metal/drug cocktail. Attenuating effect of a selenium-enriched diet.
Food Chem Toxicol
September 2024
Departamento de Bioquímica y Biología Molecular, Universidad de Córdoba, Edificio Severo Ochoa, Campus de Rabanales, Ctra. Madrid-Cádiz Km 396, 14014, Córdoba, Spain. Electronic address:
Real-life pollution usually involves simultaneous co-exposure to different chemicals. Metals and drugs are frequently and abundantly released into the environment, where they interact and bioaccumulate. Few studies analyze potential interactions between metals and pharmaceuticals in these mixtures, although their joint effects cannot be inferred from their individual properties.
View Article and Find Full Text PDFHesperidin: Enrichment, forced degradation, and structural elucidation of potential degradation products using spectral techniques.
Rapid Commun Mass Spectrom
October 2023
Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Article Synopsis
- Hesperidin (HES) is a natural substance found in citrus fruits that has been used to help prevent and treat COVID-19 and other health issues, like varicose veins.
- Scientists tested how stable HES is when it’s exposed to different conditions like heat, acid, and light to understand how its quality might change over time.
- They discovered that HES breaks down into different substances under these conditions, and some of these breakdown products were found to be short-lived and not harmful.
Sub-nanometric High-Entropy Alloy Cluster: Hydrogen Spillover Driven Synthesis on CeO and Structural Reversibility.
JACS Au
August 2023
Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan.
High-entropy alloy (HEA) nanoparticles (NPs) have attracted significant attention as promising catalysts owing to the various unique synergistic effects originating from the nanometer-scale, near-equimolar mixing of five or more components to produce single-phase solid solutions. However, the study of sub-nanometer HEA clusters having sizes of less than 1 nm remains incomplete despite the possibility of novel functions related to borderline molecular states with discrete quantum energy levels. The present work demonstrates the synthesis of CeO nanorods (CeO-NRs) on which sub-nanometer CoNiCuZnPd HEA clusters were formed with the aid of a pronounced hydrogen spillover effect on readily reducible CeO (110) facets.
View Article and Find Full Text PDFSynthesis and photothermal performance of non-stoichiometric molybdenum oxide (MoO) prepared by gamma radiation.
Dalton Trans
June 2023
Dep. Química Fundamental, Universidade Federal de Pernambuco, 50670-901, Recife, PE, Brazil.
This work reports the interaction of γ-rays with MoO in several solvents to obtain non-stoichiometric (sub-oxide) MoO through a one-pot synthesis. The effect of different doses of γ-radiation (30-90 kGy) with different protic solvents (water, ,-dimethylformamide and formic acid) was investigated. Structural modifications were characterized by X-ray diffractometry and scanning electron microscopy while optical properties were investigated by UV-Vis spectroscopy.
View Article and Find Full Text PDFThe Beneficial Impact of the Black Chokeberry Extract against the Oxidative Stress in the Sublingual Salivary Gland of Rats Intoxicated with Cadmium.
Oxid Med Cell Longev
March 2022
Department of Gerostomatology, Medical University of Bialystok, Bialystok 15-286, Poland.
Cadmium (Cd) is one of the most harmful xenobiotics to which humans are exposed, mainly by the oral route, throughout life. Preventive strategies are searched as low intoxication with this element, among others due to its prooxidative properties, can be deleterious to health and the exposure to it is continuously increasing. Recently, interest has been paid to plant raw materials with a high antioxidative potential to oppose the prooxidative properties of cadmium, such as black chokeberry ( L.
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