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An effective strategy with tofacitinib for the management of focal myositis with rheumatoid arthritis: a case report.
Front Immunol
January 2025
Department of Rheumatology and Immunology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, China.
Focal myositis is a rare, localized, benign, self-limiting, and non-suppurative inflammatory lesion of the skeletal muscle that may occasionally occur as a complication of rheumatic diseases. This case report discusses a 58-year-old patient with rheumatoid arthritis, who was diagnosed with focal myositis during standard immunosuppressive therapy. The patient was treated with tofacitinib; to our knowledge, this is the first reported case of focal myositis managed with this medication.
View Article and Find Full Text PDFAdvance in the pathogenesis of otitis media with effusion induced by platelet-activating factor.
Sci Prog
October 2024
Department of Otolaryngology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
A non-suppurative inflammatory disease of the middle ear with middle ear effusion and conductive hearing loss is called otitis media with effusion. Poor eustachian tube function, immunological factors, viral factors, and other factors are primarily involved in its pathophysiology, which has not yet been completely understood. Several researcher scholars have recently studied platelet-activating factor and they found that platelet-activating factor is closely associated to the occurrence, development, and outcome of otitis media with effusion.
View Article and Find Full Text PDFLong-term antibiotic prophylaxis for prevention of rheumatic fever recurrence and progression to rheumatic heart disease.
Cochrane Database Syst Rev
September 2024
Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
Background: Rheumatic fever is a non-suppurative, inflammatory sequela of group A Streptococcus pharyngitis that can occur at two to four weeks after infection. Following an episode of rheumatic fever, there is a risk of developing rheumatic heart disease (RHD) later in life that carries significant risk of morbidity and mortality. RHD remains the largest global cause of cardiovascular disease in the young (age < 25 years).
View Article and Find Full Text PDFChronic Diffuse Sclerosing Osteomyelitis of the Mandible: The Use of Bisphosphonates as a Treatment for a Rare and Challenging Condition.
Medicina (Kaunas)
May 2024
Department of Medical, Surgical and Health Sciences, University of Trieste, 34100 Trieste, Italy.
Article Synopsis
- Chronic diffuse sclerosing osteomyelitis is a rare bone disease that causes jaw pain and swelling, often without previous injury or obvious causes.
- Two case studies described patients experiencing recurrent jaw-related pain and swelling, leading to extensive diagnostic tests that confirmed the condition after excluding other factors.
- Treatment with bisphosphonates resulted in full symptom recovery, suggesting they may be effective in managing this condition, though more research is needed to understand it better and improve treatment options.
Surgery combined with photodynamic therapy for the case of perifolliculitis capitis abscedens et suffodiens: A case report.
SAGE Open Med Case Rep
June 2024
Department of Dermatology, Guiqian International General Hospital, Guiyang, China.
Article Synopsis
- Perifolliculitis capitis abscedens et suffodiens (dissecting cellulitis of the scalp) is a rare, chronic condition that affects hair follicles on the scalp and can significantly impact a person’s quality of life.
- Treatment options are diverse and often challenging to navigate.
- A case study of a 19-year-old male showed positive results from a combination of surgery and photodynamic therapy, particularly for those who did not respond well to traditional treatments.
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