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Agents That Came in From the Cold: Enflurane, Isoflurane, Desflurane, and Sevoflurane.
Anesth Analg
January 2025
From the Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Identification of key potassium channel genes of temporal lobe epilepsy by bioinformatics analyses and experimental verification.
Front Neurol
July 2023
Department of Emergency, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
One of the most prevalent types of epilepsy is temporal lobe epilepsy (TLE), which has unknown etiological factors and drug resistance. The detailed mechanisms underlying potassium channels in human TLE have not yet been elucidated. Hence, this study aimed to mine potassium channel genes linked to TLE using a bioinformatic approach.
View Article and Find Full Text PDFExposure to halogenated ethers causes neurodegeneration and behavioural changes in young healthy experimental animals: a systematic review and meta analyses.
Sci Rep
May 2023
Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Geert Grooteplein-Noord 21, route 126, 6525 GA, Nijmegen, The Netherlands.
The FDA issued a warning that repeated and prolonged use of inhalational anaesthetics in children younger than 3 years may increase the risk of neurological damage. Robust clinical evidence supporting this warning is however lacking. A systematic review of all preclinical evidence concerning isoflurane, sevoflurane, desflurane and enflurane exposure in young experimental animals on neurodegeneration and behaviour may elucidate how severe this risk actually is PubMed and Embase were comprehensively searched on November 23, 2022.
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