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PLoS One
January 2025
National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Introduction: Haemodynamic atrioventricular delay (AVD) optimisation has primarily focussed on signals that are not easy to acquire from a pacing system itself, such as invasive left ventricular catheterisation or arterial blood pressure (ABP). In this study, standard clinical central venous pressure (CVP) signals are tested as a potential alternative.
Methods: Sixteen patients with a temporary pacemaker after cardiac surgery were studied.
Chaos
January 2025
School of Physics and Electronic Engineering, Jiangsu Normal University, Xuzhou 221116, China.
The precise amplitude and period of neuronal oscillations are crucial for the functioning of neuronal networks. We propose a chain model featuring a repulsive coupling at the first node, followed by attractive couplings at subsequent nodes. This model allows for the simultaneous regulation of both quantities.
View Article and Find Full Text PDFJ Neurophysiol
January 2025
Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington.
The persistent Na current (I) is thought to play important roles in many brain regions including the generation of inspiration in the ventral respiratory column (VRC) of mammals. The characterization of the slow inactivation of I requires long-lasting voltage steps (>1 s), which will increase intracellular Na and activate the Na/K-ATPase pump current (I). Thus, I may contribute to the previously measured slow inactivation of I and the generation of the inspiratory bursting rhythm.
View Article and Find Full Text PDFEur Heart J Case Rep
January 2025
Cardiac Electrophysiology, National Medical Center 'November 20th', ISSSTE, Av. Felix Cuevas #540, Col. Del Valle Del. Benito Juarez, C.P. 03100 Mexico City, Mexico.
Background: The 'univentricular' heart encompasses a variety of congenital cardiac defects characterized by a single functional ventricle and an underdeveloped ventricular chamber. Surgical intervention, typically in infancy or childhood, aims to regulate pulmonary blood flow volume. In adulthood, untreated patients may experience limitations in physical activity and elevated morbidity due to persistent cyanosis and arrhythmias, notably after the Fontan procedure.
View Article and Find Full Text PDFJACC Cardiovasc Interv
January 2025
Clinic for General and Interventional Cardiology/Angiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany. Electronic address:
Background: As transcatheter aortic valve replacement is performed increasingly in younger, low-risk patients, the need for commissural alignment and coronary access has increased. Design elements of the JenaValve Trilogy (JVT) transcatheter heart valve (THV) ensure both.
Objectives: This study sought to evaluate the outcome of patients with aortic stenosis (AS) treated with this novel transfemoral, self-expanding THV.
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