The wet-bed syndrome.

S Afr Med J

Published: October 1973

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Patients with overactive bladder syndrome-wet (OAB-wet) experience urgency urinary incontinence, particularly urinary frequency and nocturia. Nocturnal enuresis (NE) is less addressed among OAB-wet patients. The study evaluated the prevalence of NE, lower urinary tract symptoms (LUTS), urodynamic factors, and social factors in OAB-wet patient.

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Early Positive Report of Viloxazine for a Child with Hyperkinetic Autism.

Psychopharmacol Bull

January 2025

Alamiri, MD, ABPN, ScD, Al-Manara CAP Centre, Kuwait Centre for Mental Health (KCMH), Shuwaikh, State of Kuwait.

Herein, authors report on an ASD child with comorbid ADHD, ID, metabolic syndrome and nocturnal enuresis that failed multiple trials of psychotropic agents for behavioural dyscontrol. Viloxazine adjuventia brought about remarkable improvement spanning different domains. Purported pharmacodynamic mechanisms are briefly discussed.

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Article Synopsis
  • The study investigates the link between childhood enuresis (bedwetting) and overactive bladder syndrome (OAB) in adult women, focusing on their sleep quality.
  • Results showed that women with OAB had a significantly higher prevalence of childhood enuresis (52.3%) compared to those without (25.6%) and reported poorer sleep quality and increased fatigue.
  • The findings suggest a strong association where childhood enuresis may increase the risk of developing OAB, which in turn is linked to sleep disorders, highlighting the importance of addressing these issues in women's health.
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Nocturia is defined as the nocturnal frequency of one or more voiding episodes per night. It increases with aging and has an impact on sleep quality and the risks of falling and mortality. Nocturia disorder involves nighttime frequency, nocturnal polyuria, and nocturnal enuresis.

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Article Synopsis
  • Parasomnias and sleep-related movement disorders (SRMD) are sleep disorders that can be triggered by certain medications, and this study aimed to review the literature on this association from January 2020 to June 2023.
  • Over 900 records were examined, identifying 73 drugs linked to common drug-induced parasomnias like nightmares and sleepwalking, as well as SRMDs such as restless legs syndrome and bruxism.
  • The study discusses potential mechanisms behind these disorders related to various neurotransmitters, including the impact of antipsychotics, opioids, and medications affecting serotonin, noradrenergic, and dopamine pathways, highlighting gaps in drug labeling for these conditions.
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