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() is a major bacterial pathogen associated with many cases of serious infections, such as urinary tract infections (UTI) and meningitis intestinal. The rapid emergence of antimicrobial multidrug-resistant bacteria occurring worldwide has been attributed to the overuse of antibiotics. Alternative strategies must be developed to overcome antibiotic resistance.

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Aims: To describe the historical changes from antiquity until present in the presentation and treatment of male urinary incontinence.

Methods: A literature review of PubMed articles in English pertaining to male incontinence was performed.

Results: Male urinary incontinence was first mentioned in Egyptian manuscripts in 1500 B.

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Urethral injection therapy for urinary incontinence in women.

Cochrane Database Syst Rev

July 2017

Department of Urology, Sunderland Royal Hospital, Kayll Road, Sunderland, Tyne & Wear, UK, SR4 7TP.

Background: Urinary incontinence imposes a significant health and economic burden to society. Periurethral or transurethral injection of bulking agents is a minimally invasive surgical procedure used as one the surgical treatments of stress urinary incontinence (SUI) in adult women.

Objectives: To assess the effects of periurethral or transurethral injection therapy on the cure or improvement of urinary incontinence in women.

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Stress urinary incontinence (SUI) affects a large proportion of middle-aged and elderly women. When all conservative means are ineffective, a surgical treatment including retropubic suspension, pubovaginal and tension-free slings, is contemplated. Intra-urethral injections with bulking agents have been used as an alternative to the mentioned surgical procedures with alternate results.

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Background: Periurethral or transurethral injection of bulking agents is a minimally invasive surgical procedure used for the treatment of stress urinary incontinence in adult women.

Objectives: To assess the effects of periurethral or transurethral injection therapy on the cure or improvement of urinary incontinence in women.

Search Methods: We searched the Cochrane Incontinence Group Specialised Trials Register (searched 8 November 2010) and the reference lists of relevant articles.

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