Endocardial monophasic active potentials (M.A.P.) recorded by suction --tip intracardiac catheters constitute a new research-- method in cardiac arrythmias, electrophysiology and pharmacology. The characteristics of MAP at auricular and ventricular levels are analyzed. The limitations of the method in its incapacity to record the MAP of conduction tissues is discussed. This method of recording MAP is evaluated with antiarrythmic drugs of tipes I, II, III and IV. The results are identical to recordings performed with intracellular microelectrodes.
Download full-text PDF |
Source |
---|
JACC Clin Electrophysiol
August 2023
Department of Cardiovascular Sciences, Cardiovascular Imaging and Dynamics, KU Leuven, Leuven, Belgium. Electronic address:
Background: Spatial heterogeneity in repolarization plays an important role in generating and sustaining cardiac arrhythmias. Reliable determination of repolarization times remains challenging.
Objectives: The goal of this study was to improve processing of densely sampled noncontact unipolar electrograms to yield reliable high-resolution activation and repolarization maps.
Zhonghua Xin Xue Guan Bing Za Zhi
November 2022
Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
To determine the electrophysiological effects and related mechanisms of late sodium current inhibitors on hearts with short QT intervals. The electrophysiological study was performed on isolated Langendorff perfused rabbit hearts. A total of 80 New Zealand White rabbits were used and 34 hearts without drug treatment were defined as control group A, these hearts were then treated with I opener pinacidil, defined as pinacidil group A.
View Article and Find Full Text PDFJ Cardiovasc Electrophysiol
May 2022
Medanta The Medicity, Gurugram, New Delhi, India.
Background: Localization of atrioventricular accessory pathways (AP) from Electrocardiogram (ECG) is crucial for successful ablation. We analyzed the value of limb lead 2 versus 3 QRS vector discordance on surface ECG among right-sided pathways.
Methods: Data from consecutive patients undergoing successful ablation of manifest AP were analyzed.
Alterations of the transmural gradient of repolarization may contribute to the increase of transmural dispersion of repolarization and ventricular arrhythmias. The transmural gradient of repolarization may play an important role in sudden death associated with left ventricular epicardial pacing. To investigate the changes of transmural gradient dispersion of ventricular repolarization with different pacing sites in heart failure (HF) canines, 8 mongrel dogs were randomized into healthy group and HF group (n = 4).
View Article and Find Full Text PDFJ Cardiothorac Surg
June 2020
Pediatric Cardiology Department, Prince Sultan Cardiac Center, Prince Sultan Military Medical City, As Sulimaniyah, Riyadh, 12233, Saudi Arabia.
Background: Fetal aortic stenosis may progress to hypoplastic left heart syndrome (HLHS), which carries a poor prognosis. We report two infants with fetal aortic stenosis successfully treated with fetal aortic valvuloplasty (FAV) using balloon dilatation.
Case Presentation: Of five fetuses with aortic stenosis fulfilling the FAV criteria of severe aortic stenosis with a left ventricular length Z-score of ≥ - 2, retrograde flow in the transverse aortic arch, left-to-right flow across the foramen ovale, monophasic mitral inflow, and significant left ventricular dysfunction, we obtained permission for FAV in two fetuses.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!