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LINC01224 promotes the Warburg effect in gastric cancer by activating the miR-486-5p/PI3K axis.
In Vitro Cell Dev Biol Anim
January 2025
Gastroenterology Section, Medical Center of Digestive Disease, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, China.
The Warburg effect, a common feature of solid tumors, rewires the metabolism and promotes growth, survival, proliferation, and long-term maintenance in gastric cancer (GC). We performed in vitro and in vivo studies of the pathogenesis of GC to investigate the effects and mechanism of LINC01224 in this cancer. qRT-PCR was used to measure the expression of LINC01224 or miR-486-5p in GC cells, and the expression of LINC01224 in GC tissues by FISH (Fluorescence in situ hybridization) analysis was evaluated.
View Article and Find Full Text PDFBRN3A, a transcription factor, regulates the expression of genes involved in biological processes shaping the HPV induced cervical cancer.
Genes Genomics
January 2025
Cytogenetics Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, India.
Background: Cervical cancer is the fourth most common cancer worldwide in females. This occurs primarily due to the infection of high-risk Human Papilloma Virus (HPV), although in advanced stages it requires support from host cellular factors. BRN3A is one such host cellular factors, whose expression remains high in cervical cancers and upregulates tumorigenic HPV gene expression.
View Article and Find Full Text PDFAcute and acute-on-chronic liver failure: Pathogenesis, management and perspectives.
Liver Int
February 2025
Department of Infectious Diseases, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai, China.
Expression profile analysis of estrous-phased ovarian tissue of high and low prolific lines of inbred Swiss albino mice.
Mol Biol Rep
January 2025
Division of Animal Genetics, ICAR-Indian Veterinary Research Institute (ICAR-IVRI), Izatnagar, Bareilly 243 122, Uttar Pradesh, India.
Background: Litter size in mice is an important fitness and economic feature that is controlled by several genes and influenced by non-genetic factors too. High positive selection pressure in each generation for Litter size at birth (LSB), resulted in the development of high and low prolific lines of inbred Swiss albino mice (SAM). Despite uniform management conditions, these lines showed variability in LSB across the generation.
View Article and Find Full Text PDFSkin cancer knowledge, attitudes, beliefs, and prevention practices among beachgoers: a narrative review.
Arch Dermatol Res
January 2025
Department of Dermatology, School of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216-4505, USA.
People who spend time at the beach at increased risk for ultraviolet light (UV) exposure. This review assessed skin cancer-related knowledge, attitudes, beliefs, and prevention practices among beachgoers and sunbathers at the beach. Relevant articles were search in the following electronic databases: PubMed (Medline), Cumulative Index to Nursing and Allied Health (CINAHL), ERIC, and PsycINFO.
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